Adaquine or Cartophen?
Joyce Culligan
back legs, other than that she is quite healthy. People have suggested I put
her on Predisone, which I would prefere not to do given it is a steroid and
his hard on the kidneys and such (why speed up the process!). Vets have been
using adaquine (sp?) and cartrophen (sp?) non-steroids, which in many cases
have had significant results.
My question to this forum is
a) has anyone had experience with these injections and, if so, what is your
opinion - be it positive OR negative;
b) cost of injections (approximately);
c) any other alternatives that you know of.
Thanks for your time
Joyce Culligan
CULL...@BLDGUMSU.LAN1.UMANITOBA.CA
Lori May
>I have a 13 year old Siberian Husky who has become fairly arthritic in her
>back legs, other than that she is quite healthy. People have suggested I put
>her on Predisone, which I would prefere not to do given it is a steroid and
>his hard on the kidneys and such (why speed up the process!). Vets have been
>using adaquine (sp?) and cartrophen (sp?) non-steroids, which in many cases
>have had significant results.
>
>My question to this forum is
>
>a) has anyone had experience with these injections and, if so, what is your
>opinion - be it positive OR negative;
>
but they have helped him tremendously. He was diagnosed with moderate
hip dysplasia but with the help of Adequan we have not had to do surgery
yet. He received on injection per week for three weeks, then was allowed
to go until his symptoms (limping, lameness) showed up. That was six
weeks. He now has the time extended to eight weeks between shots. He
showed improvements after the second shot and now improves after he
receives each shot.
>b) cost of injections (approximately);
>
My vet charges $35 per shot.
>c) any other alternatives that you know of.
Many people use Cosequin (oral form of the same ingredient as Adequan) or
Glycoflex, a food supplement mapped from green-lipped mussels.
h...@sirius.com
>
> My question to this forum is
>
> a) has anyone had experience with these injections and, if so, what is your
> opinion - be it positive OR negative;
>
inconclusive - meaning the dog didn't experience any positive or negative results.
There were two vets in the office, with each trying Adaquine on their own dogs.
One thought it was a useful medication, the other said it had no effect on hers.
After the [I believe] five injections program, we took her off it, and I then put her
on Glycoflex. Almost immediately (within two days) she began displaying
remarkable agility progress on the Glycoflex. She was on Glycoflex for about
a year before she died, and in that time her arthritis never seemed to hinder her
as before the Glycoflex.
>
> b) cost of injections (approximately);
>
program consisted of five injections. It would have been worth the world, had they
worked.
>
> c) any other alternatives that you know of.
>
>>>>
Regards and Good Luck,
____________________________________________________
Howard Perry
h...@sirius.com, h...@netcom.com,or h...@well.sf.ca.us
http://www.well.com/www/hbp/
http://www.io.com/user/hbp/folkdance/fd.html
____________________________________________________
Sheila M. Slife
stores called glucosamine sulfate (GS). I don't recall the brand name
offhand as I'm at work but it costs about $25.00 for a bottle that will
last my male Golden about a month or so depending on how many I dose per
day. If you'd like to know more please email me at ssl...@pclan.utsa.edu
or to this list.
Shari Bernhard
>In article <culligan.1...@bldgumsu.lan1.umanitoba.ca> cull...@bldgumsu.lan1.umanitoba.ca (Joyce Culligan) writes:
>>I have a 13 year old Siberian Husky who has become fairly arthritic in her
>>a) has anyone had experience with these injections and, if so, what is your
>>opinion - be it positive OR negative;
>>
>but they have helped him tremendously. He was diagnosed with moderate
>hip dysplasia but with the help of Adequan we have not had to do surgery
>yet. He received on injection per week for three weeks, then was allowed
>to go until his symptoms (limping, lameness) showed up. That was six
>weeks. He now has the time extended to eight weeks between shots. He
>showed improvements after the second shot and now improves after he
>receives each shot.
>>b) cost of injections (approximately);
>>
>My vet charges $35 per shot.
>>c) any other alternatives that you know of.
>Many people use Cosequin (oral form of the same ingredient as Adequan) or
>Glycoflex, a food supplement mapped from green-lipped mussels.
(Hi, Lori!) I switched Raven from Adequan shots (the shots themselves
seemed to make her more lame) to GlycoFlex which my vet special ordered
for me. Then another client of hers asked for them. GF has worked
quite well for Raven's arthritis, although it isn't her only problem.
I have noticed an improvement in her ability to stand up and she seems
spunkier in general. She also eats them like they were a treat! On the
downside, they smell awful and make me gag when I open the container.
It doesn't bother my husband so now it's *his* job!
Glad your Rottie (Ricky?) is doing well, Lori.
/========================================================================\
|| Shari Bernhard *** Built for comfort, not for speed *** ~O~ ||
|| sh...@modcomp.com <_> ||
|| <|> ||
|| | ||
|| Mom to: Raven the WonderDog, Frieda the Hurricane Andrew RescuedDog, ||
|| and Ginger the Dancing Dachshund (what a very cute dog!) ||
|| Sweet kitties Gray One, White One, Little One and Cassandra! ||
\========================================================================/
Jim Budet
>>
>My Rottweiler has been on Adequan injections for a year. I was skeptical,
>but they have helped him tremendously. He was diagnosed with moderate
>hip dysplasia but with the help of Adequan we have not had to do surgery
>yet. He received on injection per week for three weeks, then was allowed
>to go until his symptoms (limping, lameness) showed up. That was six
>weeks. He now has the time extended to eight weeks between shots. He
>showed improvements after the second shot and now improves after he
>receives each shot.
I have a question about the use of Adequan for hip dysplasia. Does
this drup have any effect on the dysplasia itself, or is it aimed at
keeping the joint deteriation down, or to keep the pain down or
something else?
In other words, if a dog has hip dysplasia and responds very well to
Adequan. Will a new X-ray reveal that the dysplasia has improved?
I'm really confused about this so I'll re-word it yet another way.
Is Adequan used to treat the dysplasia or the side effects of having
hip dysplasia.
Thanks.
--
/\ /\ /\ |
/ \/ \/ \ Jim Budet | CIS: 7317...@compuserve.com
/ \ \ \ UniSQL, Inc. |
\ / / / Austin, TX | DISCLAIMER: The content of this
\ /\ /\ / jim....@unisql.com | message are solely my opinion
\/ \/ \/ | (of which I have many).
--
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Jim Budet (jbudet x136)
Janice Swenson
after dysplasia is diagnosed to slow up the degeneration
of the joints or in cases stop the degeneration of the joint.
It generally depends on how advanced the dysplasia is
before treatment is started. Dogs develop pain with the
loss of synovial fluid in the joint and the loss of articular
cartilage. Adequan protects against the loss of synovial
fluid and thus the loss of articular cartilage in the joint.
This slows or stops the advance of osteoarthritis. So, it
helps the side effects of dysplasia. The pain the dog has
ends up being reduced or be nonexistent. The movement
is improved.
On the otherhand, study results have shown that young dogs
predisposed to hip dyplasia given adequan had significantly
better hip conformation that did untreated dogs.
So, there is evidence that adequan is beneficial in the prevention
and treatment of osteoarthritis and hip dysplasia.
The study information is in April 15, 1994 Journal American
Veterinary Medicine "Polysulfated glycosaminoglycan in the
treatment of osteoarthritis."
-
Janice Swenson WPA...@prodigy.com
Admiral (newf, Therapy Pet Pals of TX)
Bianca (pyr, Therapy Pet Pals of TX)
Linsey (newf, I'm still learning)
Shelby (terrier terrorist)
Joel Levinson
J
JC>I have a 13 year old Siberian Husky who has become fairly arthritic in her
>back legs, other than that she is quite healthy. People have suggested I pu
>his hard on the kidneys and such (why speed up the process!). Vets have bee
>have had significant results.
JC>My question to this forum is
JC>a) has anyone had experience with these injections and, if so, what is your
>opinion - be it positive OR negative;
yes - I have a three year old OES who has been on an oral form of
adequan since he was 10 months old.
JC>b) cost of injections (approximately);
Depending on your vet, 25 to 35 dollars per.
JC>c) any other alternatives that you know of.
after the initial round of five injections of adequan, we went to an
oral form of the drug. The version we are currently using is called
disc discovery. Cosequin and glycoflex are the most popular.
JC>Thanks for your time
JC>Joyce Culligan
>CULL...@BLDGUMSU.LAN1.UMANITOBA.CA
---
* QMPro 1.53 * On the Internet, nobody knows you're a dog.
Joyce Culligan
>From: WPA...@prodigy.com (Janice Swenson)
>Subject: Re: Adaquine or Cartophen?
>Date: 21 Apr 1995 21:59:55 GMT
Many thanks to all of you who wrote regarding their choices and comments on
Adequin.
As a summary for those who were also interested in my "findings" I note the
following:
All who wrote (around 10 or 12) had dealings with Adequine or a nutrient
supplement like Glycoflex. Of those who used Adequine most noted results, I
believe only one did not and then put the dog on Glycoflex and then noted
results.
Adequine appears to have been mainly used on dogs that were dysplastic.
As for Cartrophen: None of you who wrote mentioned this option.
As I understand from our Vets here in Canada, is a fairly new shot, similar to
Adequine, but more specifically for Osteoarthritis. I have heard that these
shots are quite effective, usually a dog needs fewer shots and they are
less expensive (ranging from 15 - 22 Canadian Dollars for a dog around 50-55
lbs).
I decided to try Cartrophen because my dog does not suffer from any
dysplasia, but just arthritis and because here too there are some very
positive results.
I am quoting parts of the text in the pamphlet that was given to me with
regard to Cartrophen for your information:
What is Oseoarthritis. . . .
"Dogs of any age can be afflictied, although the condition is prevalent in
older pets. Symptoms can be stiffening up and reduced activity, apearing to
be due to "old age" and untreatable. The dog may not be lame in any one leg,
but have pain in all joints, or have different joins lame. ......
Normal healthy cartilage covers the end of the long bones and, in conjunction
with synovial fluid, provides an almost fritionless, wear resistant,
weight-bearing surface. In osteoarthritis, the cartilage is eroded away and
the synovial fluid which lubricates the joint thins out, resulting in a
further loss of mobility. Movement is also restricted by swelling of the
joints. All of these factors combine and compound to cause your dog
discomfort and pain.
Conventional treatment for osteoarthritis is with cortisone and non-steroid
anti-imflammatory drugs, used in humans as well as animals. These drugs can
oly reduce the swelling and pain of affected joints and need to be
administrered continously. This is both expensive and inconvenient.
Sometimes, the use of thes drugs may encourage overexertion of the affected
joint- in turn, accelerating the degenerative process. Chronic use of some of
these drugs has been reported to accelerate joint destructions mainly due to
the inhibition of celluar repair processes.
CARTROPHEN VET is an injection administered by your vet. It has negligible
side effects and works to retard the progression of arthritis in your pet.
.....it is a revolutionary advane in the treatment of osteoarthritis and
musculoskeletal disead in dogs. It relieves pain and lameness and increases
the range of pain-free movement by treating the UNDERLYING DISEASE PROCESS -
NOT JUST THE SYMPTOMS (emphasis mine).
It has multiple pharmacological actions which affect the immune and tissue
cell systems which include:
- inhibition of enzymes which break down cartilage in addition to stimulating
natural inhibitors of these destructive enzymes..
- stimulation of the production of lubricant and cartilage molecules by the
joint cells...
- improvement of the circulation fo blood to the arthritic tissues, thus
improving nutirion ot the joint tissues...
- normalisation of the immune response by regulating the messenger molecules
which control these processes.
- stimulation of the production of proteins which block damaging free radicals
and antigens.
SIDE EFFECTS:
In very rare cases, dogs with undiagnosed cancer have collapsed after
treatment.
TREATMENT:`
Treatment is similar to vaccinations, with a course of weekly doses for four
weeks. This is followed by booster applications at intervals of about one
year, although this will vary between individual cases. Most pets are very
quick to respond to the initial couse with an increase in activity and general
well-being. Eighty per cent of dogs treated respond to the therapy (they
studied 70,000 cases - good sampling I'd say!)
NOTE: You may not see immediate relief after the first injection. In order
for your dog to obtain full benefit from the treatment, it is very important
to complete the course that has been recommended by your vet.
LauraW DVM
the same material that is made by the synovium(joint membranes) to cushion
and protect the joint. If you re-xray your dog there will not be an
improvement in the disease. The only "cure" is surgery. If your dog is
small (under 30 lbs) you can have the femoral head removed so that there
is not the constant abrasion at the femur - hip joint. In a young dog
with no arthritis / degenerative joint disease you can do a triple pelvic
osteotomy - have the pelvis broken in 3 places and repositioned so that
the femoral heal sits within the acetabulum (hip joint) in a mote normal
position. The dog needs to be under a year old for this to work (hasn't
finished developing yet). The final option is a total hip replacement (
best for large dogs) where the femoral head is reomved and replaced woth
a steel one and a matching acetabular cup is also placed - no arthritis,
no rubbing, pain free once recovered completely from surgery. The two
surgery options TPO and total hip are expensive - it takes anywhere from
4-8 hours of surgery to do either. The dogs also need physical therapy
afterward. All people I've spoken to who have done this are happy with
the results.
If you have any questions please feel free to contact me aol.(LauraW
DVM@aol)
Laura W DVM.