Dog - Treatment for Vitiligo (Leucoderma)
mlv
just coming up to 2-years-old.
Over the past 2 months or so, she has started to develop pale (almost white)
patches on her nose, lips, eyelids and jowls. Onset of this problem seems
to have coincided with her being spayed.
The problem is the skin pigmentary disorder Vitiligo, also known as
leucoderma or achromia, which is the loss of skin-pigmentation (melanin).
Does anyone know of an effective treatment or cure for this disorder?
TIA
--
Mike
-Please remove 'safetycatch' from email address before firing off your
reply-
gly...@gmail.com
> leucoderma or achromia, which is the loss of skin-pigmentation (melanin).
>
> Does anyone know of an effective treatment or cure for this disorder?
I'm not sure that one exists for people, nevermind dogs. The
treatment for people seems to be mostly to stay out of the sun or wear
heavy sunscreen so that the contrast is less noticeable. A quick
google shows that most of what's being pandered out there are herbal
remedies and pigmented oils, nothing "medical".
My only suggestion would be to keep her out of the sun as much as you
can, watch for burns, and maybe rub sunscreen into those areas that
tend to get burned (but I don't know how effective that'd be on the
nose, lips and jowls, or if it'd simply get licked off).
Good luck,
--Glenn Lyford
Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory
"mlv" <mike.safety...@jet.co.uk> wrote in message
news:g6c3sb$61n$1...@north.jnrs.ja.net...
Welcome to The Sincerely Incredibly Freakin Insanely
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and security specializing in temperament and behavior
problems and protection <{}: ~ ) >
Here's your own FREE COPY of The Sincerely Incredibly
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The actual INSTRUCTION begins on the third page "*777*
Wits' End Method", abHOWET 1/4 down the page starting
with "Here's ALL the INFORMATION you NEED" and my
phone # and instructions to CALL ANY TIME.
There you will find ALL the FREE information you need
to pupperly handle raise and train your pets and family.
Just follow the instructions PRECISELY and ASK me if
you need any additional FREE HEELP <{}': ~ ) >
You'll likeWIZE find ETHICAL nutrition and heelth
care practices taught on the heelth page of my website.
> I took on a rescue Black & Tan Doberman bitch about 9 months ago. She is
> just coming up to 2-years-old.
>
> Over the past 2 months or so, she has started to develop pale
> (almost white) patches on her nose, lips, eyelids and jowls.
> Onset of this problem seems to have coincided with her being spayed.
Surgical sexual mutilation INCREASES phobic and
hyperactive behaviors. There AIN'T NO benefit to
"neutering" other than for the veterinary malpracticioners
who PROFIT from SHELTER / RESCUE abusers who
likeWIZE PROFIT from SELLIN mutilated dogs to
caring unsuspecting ignorameHOWESES, otherWIZE,
there's BE NO overpupulation problem, after nearly thirty
years of SHELTER / RESCUE Spay / Neuter Nazi genocide:
Here's a few FACTS the pathetic miserable stinkin rotten lyin
animal murderin punk thug coward active acute chronic life-
long incurable malignant maliciHOWES MENTAL CASES
and veterinary malpracticioners you're askin for advice DON'T
WANT YOU TO KNOW:
"Unlike what you will find in Spay/Neuter Fact Sheets,
the health impacts of spay/neuter that are discussed in
this paper are all backed up with citations to the veterinary
medical literature. You can find the paper here:
http://escregistry.kattare.com/healthEffectsOfSpayNeuterInDogs.pdf
Material that includes research data from 2006, 2005
was presented at ACC&D's Third International Symposium,
and part of the slideshows presentedare available here:
http://www.acc-d.org/2006%20Symposium%20Docs/Session%20I.pdf
Issues regarding previous assumptions on what neutering
does as a 'benefit' are pretty well challenged in this data above.
Alliance for Contraception in Cats and Dogs (ACC&D) is a
nonprofit 501C(3) group involved in attempting to study, define
and resolve some of the problems that currently exist internationally
as they regard issues of animal population control.
"More than 120 representatives from universities, animal welfare
organizations, foundations, companies, and government agencies
from 11 countries gathered to share information and plan for the
future". Main site: http://www.acc-d.org/
"On the negative side, neutering male dogs if done before maturity,
increases the risk of osteosarcoma (bone cancer) by a factor of 3.8;
this is a common ancer in medium/large and larger breeds with a
poor prognosis.
increases the risk of cardiac hemangiosarcoma by a factor of 1.6;
this is a common cancer and major cause of death in some breeds
triples the risk of hypothyroidism
increases the risk of geriatric cognitive impairment
triples the risk of obesity, a common health problem in dogs with
it the many associated health problems associated with obesity
· quadruples the small risk (<0.6%) of prostate cancer
· doubles the small risk (<1%) of urinary tract cancers
· increases the risk of orthopedic disorders
· increases the risk of adverse reactions to vaccinations
Hemangiosarcoma is a common cancer in dogs. It is a major
cause of death in some breeds, such as Salukis, French Bulldogs,
Irish Water Spaniels, Flat Coated Retrievers, Golden Retrievers,
Boxers, Afghan Hounds, English Setter, Scottish Terrier, Boston
Terrier, Bulldogs, and German Shepherd Dogs24.
In an aged-matched case controlled study, spayed females were
found to have a 2.2 times higher risk of splenic hemangiosarcoma
compared to intact females24.
A retrospective study of cardiac hemangiosarcoma risk factors
found a >5 times greater risk in spayed female dogs compared
to intact female dogs and a 1.6 times higher risk in neutered male
dogs compared to intact male dogs.25
The authors suggest a protective effect of sex hormones against
hemangiosarcoma, especially in females.
In breeds where hermangiosarcoma is an important cause of
death, the increased risk associated with spay/neuter is likely
one that should factor into decisions on whether or when to
sterilize a dog.
Hypothyroidism
Spay/neuter in dogs was found to be correlated with a three fold
increased risk of hypothyroidism compared to intact dogs. The
researchers suggest a cause-and-effect relationship26.
They wrote: "More important [than the mild direct impact on thyroid
function] in the association between [spaying and] neutering and
hypothyroidism may be the effect of sex hormones on the immune
system.
Castration increases the severity of autoimmune thyroiditis in mice"
which may explain the link between spay/neuter and hypothyroidism
in dogs.
"Dr. Spain, who has been recently involved in many studies assessing
the long-term risks and benefits of early-age neutering, presented
convincing data about the effects of spay/neuter on hip dysplasia,
cranial cruciate ligament rupture, long bone development, body
weight, diabetes, urinary tract infections, mammary cancer, and
several other conditions."
CONCLUSIONS
An objective reading of the veterinary medical literature reveals
a complex situation with respect to the longterm health impacts
of spay/neuter in dogs.
The evidence shows that spay/neuter correlates with both positive
AND adverse health effects in dogs. It also suggests how much we
really do not yet understand about this subject.
On balance, it appears that no compelling case can be made for
neutering most male dogs to prevent future health problems,
especially immature male dogs. The number of health problems
associated with neutering may exceed the associated health
benefits in most cases.
----------------------------
> The problem is the skin pigmentary disorder Vitiligo, also known as
> leucoderma or achromia, which is the loss of skin-pigmentation (melanin).
>
> Does anyone know of an effective treatment or cure for this disorder?
Google has 393,000 references for Vitiligo stress
http://www.antivitiligo.com/frequently-asked-questions.html:
Vitiligo results from a derangement of your normal defense
mechanisms against infection. The body starts producing
antibodies against pigment producing cells of its own skin.
No definite causes are known, but inheritance has a role.
This is a generalized abnormality of your immune system,
and there are currently no acceptable permanent means to
halt this process
---------------
http://www.makeup-care.info/beauty/skin-problems/leucoderma.htm
The chief causes of leucoderma are said to be heavy mental stress,
chronic or acute gastric problem, and impaired hepatic function such
as jaundice or other parasites in the alimentary canal, a faulty
perspiratory mechanism, and burn injuries
http://www.skinstreet.net/vitiligo.html:
It is an auto-immune condition.
PUVA therapy enhances skin re-pigmentation. An oral psoralen
compound is given to the patient. Two hours later , the de-pigmented
patch on his body is exposed to ultraviolet-A (UVA) rays, for a fixed
time duration.
--------------------
http://www.sarkaritel.com/news_and_features/health/leucoderma.htm
Precipitating Factors:-
a) Emotional Crisis - Death in family, Loss of job , Sudden shock etc.
b) Gastro intestinal tract disorders like Worms, Jaundice, amoeboisis etc.
c) Prolonged use of Drugs ,antibiotics,Oral anovulating agents etc.
d) Local causes like trauma,burns exposure to chemicals etc.
Though the aetilogy of vitiligo is obscure, various hypothesis
are suggestive of its genesis .Among these the important ones are:-
1) Immune Hypothesis - Melanocyte destruction and dysfunction
or both may result into Hypopigmentation of vitiligo.
2) Neural Hypothesis - Neurochemical inhibitors are released at nerve
endings that destroy the melanocytes or inhibit their functioning.
3) Melanocyte Self-Destruction Hypothesis - Proposes that
an intermediate inmelanin synthesis causes melenocyte destruction.
4) Dietary deficiency of Proeins and Cupro minerals is a major
factor for causing vitiligo. Serum skin and cerebro-spinal fluid
copper levels are low in theses cases.
5) A gastro-intestinal disorder like Chronic amoeboisis,chronic
Dyspepsia and Intestinal Worms may be additional factors.
6) Use of Broad spectrum Antibiotics ,especially Chlormphenicol
and Streptomycinleads to appearanceof vitiligo.
7) Trauma or Local irritation caused by wearing the sari or Trousers
too tightly do produce vitiligo in individuals predisposed to it.
8) Acute Stress may be followed by fast spreading typeof vitiligo
proving the theory of Troponeurosis. Emotional crisis may be an
additional factor.
9) An Endocrinal disorder may be operative,Diabetes, Pernicious
anaemia, Thyrotoxicosis, Myxoedema, and Addison'sdisease may
be associated with vitiligo.
10) Composite Hypothesis - None of the theories alone is entirely
satisfactory. Actual mechanism of inhibition or destruction of
melancytes is much more complex than any of these mechanisms
suggested.
Precipitating Factors:-
a) Emotional Crisis - Death in family, Loss of job , Sudden shock etc.
b) Gastro intestinal tract disorders like Worms, Jaundice, amoeboisis etc.
c) Prolonged use of Drugs ,antibiotics,Oral anovulating agents etc.
d) Local causes like trauma,burns exposureto chemicals etc.
Pathologically :- A defect in enzyme Tyrosinase is held responsible for
vitiligo. Acording to some Dermatologists, it is a Trophoneurosis and
Melatonin, a substance secreted at nerve endings inhibits Tyrisinase, thus
interfering in pigment formation.
Clinical Presentation of Vitiligo
Localised Type:-
a) Focal - One or more maculesin two single areas but not segmented.
b) Segmental - One or more macules in a dermatomal pattern.
c) Mucosal - Involvement of mucous membrane alone.
Generalised Type :-
d) Acrofacial - Involvement of face and distal extremities.
e) Vulgaris - Scattered macules in symmetrical or asymmetrical
distribution.
Universalis- Total or nearly whole body involvement.
Is there any prevention for vitiligo ?
There are certain precautions which can dealy or stop
the onset of the disease.
1. Maintain good general health and immunity.
2. It is a non communicable disease.
3. Any patch should be thoroughly examined first.
4. Application of any unconfirmed tropical medication
on skin should be avoided.
5. Use of synthetic clothes should be restricted.
6. Avoid excess intake of Sour things.
7. Avoid Steroids.
It is a myth that leucoderma occurs by drinking milk over the fish.
There is no relevance in avoiding anything to eat or drink which is
white in colour as assumed by some people similarly in cases of
Jaundice for Yellow coloured things.
What is the Treatment for Vitiligo ?
Allopathy - Commonest drug used is Psoralen , Melanocyl etc to be use
locally followed by sun exposure. In few cases oral Antioxidants are also
being used. The latest application of Placentex is also used.UltraViolet
Rays exposure or PUVA.
Ayurveda- Local application of Babchi Oil over
the depigmented areas, Use of Coper utensils.
Others- Applying Coloured Dyes, Silver Nitrate etc .
Latest being permanent Colouring.
Surgical measures- Grafting etc.
Homoeopathy- Though Vitiligo has always puzzled physicians
of all systems of medicine. However, Homoeopathy system offers
reasonably positive treatment if not cure in all the cases.
Since it offers a comprehensive treatment as it goes to the root of
the problem by helping build up immunity and eventually restores
the pigmented patches back to the normal skin colour.
I have observed in my clinic that there are some definite connection
in the patients who are being treated for Hypothyroidism then getting
Hyperthyroidism show patches of leucoderma as drugs induced leucoderma.
> TIA
You're welcome <{}: ~ ) >
> --
> Mike
"The day may come when the rest of the animal creation
may acquire those rights
which never could have been withholden from them
but by the hand of tyranny.
The question is not can they REASON,
nor can they TALK,
but can they SUFFER?" -
- Jeremy Bentham
"Of all tyrannies, a tyranny exercised
for the good of its victims,
may be the most oppressive.
Those who torment us for our own good
will torment us without end,
for they do so with the approval of
their own conscience." -
- C.S. Lewis.
"Death is better, a milder fate than tyranny",
Aeschylus (525BC-456BC),
Agamemnon.
"If you talk with the animals, they will talk with you
and you will know each other.
If you do not talk to them, you will not know them,
and what you do not know you will fear.
What one fears, one destroys."
Chief Dan George
All truth passes through three stages.
First, it is ridiculed.
Second, it is violently opposed.
Third, it is accepted as being self-evident.
-Arthur Schopenhauer
"Thank you for fighting the fine fight--
even tho it's a hopeless task,
in this system of things.
As long as man is ruling man,
there will be animals (and humans!)
abused and neglected. :-(
Your student," Juanita.
"If you've got them by the balls
their hearts and minds
will follow,"
John Wayne.
ANY QUESTIONS, People?
"Ye shall know the truth,
and the truth shall make you mad." -
~Aldous Huxley.
"Mit der Dummheit kaempfen Goetter selbst vergebens!"
"Against stupidity the Gods themselves contend in vain!"
-Friedrich Schiller.
INDEEDY.
AND THAT'S HOWE COME THEY GOT ME NHOWE!
In Love And Light,
I Remain Respectfully, Humbly Yours,
The WORLD'S CRUELEST Trainer,
Jerry Howe,
The Sincerely Incredibly Freakin Insanely Simply
A-M-A-Z-I-N-G
*M-A-J-E-S-T-I-C*
*G-R-A-N-D*
*M-A-S-T-E-R*
Puppy, Child, Pussy, Birdy, Ferret, Goat, Monkey
SpHOWES And Horsey Wizard <{) ;~ ) >
HOWE MAY I SERVE YOU <{}; ~ ) >
Sincerely,
Jerry Howe,
Director of Research,
Human And Animal Behavior
Forensic Sciences Research Laboratory,
BIOSOUND Scientific,
Director of Training,
Wits' End Dog Training
1611 24th St
Orlando, FL 32805
Phone: 1-407-425-5092 (Call ANY TIME)
http://www.freewebs.com/thesimplyamazingpuppywizard
E-mail:
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mlv
>
> My only suggestion would be to keep her out of the sun as much as
> you can, watch for burns, and maybe rub sunscreen into those areas
> that tend to get burned (but I don't know how effective that'd be on the
> nose, lips and jowls, or if it'd simply get licked off).
Thanks for the advice.
The dog hasn't been in the sun much, so I don't know whether ultraviolet
rays are contributing towards the skin- disorder, or not. It may be an
autoimmune problem, or it may simply be genetic.
There are a couple of websites claiming a cure for vitiligo in humans (e.g.
Vitligo Tab), but unfortunately no such claims for animals.
I'll keep searching!
mlv
>
> Welcome to The Sincerely Incredibly Freakin
>
> <stanch verbal diarrhoea>
Unfortunately, any useful information that may have been contained in your
post was rendered inconspicuous by the seemingly pointless verbosity.
Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory
"mlv" <mike.safety...@jet.co.uk> wrote in message
news:g7a2pg$gor$1...@north.jnrs.ja.net...
> "Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory" wrote:
>>
>> Welcome to The Sincerely Incredibly Freakin
>> Insanely Simply...
>>
>> <stanch verbal diarrhoea>
That's KINDLY of you, mike. Your fellHOWE dog lovers here
FEAR an HATE IT when people QUOTE EVIDENCE of lies
insanity mutilation and abuse from The Sincerely Incredibly
Freakin Insanely Simply Amazing, Majestic Grand Master Puppy,
Child, Pussy, Birdy, Goat, Ferret, Monkey, SpHOWES, And Horsey
Wizard's 100% CONSISTENTLY NEARLY INSTANTLY
SUCCESSFUL FREE WWW Wits' End Training Method
Manual Forums And Human And Animal Behavior Forensic
Sciences Research Laboratory Archives <{}: ~ ) >
> Unfortunately, any useful information that may have been contained in your
> post was rendered inconspicuous by the seemingly pointless verbosity.
You mean that you're EMBARRASSED ASHAMED an
HUMILIATED to realize that YOU and your veterinary
malpracticioner have CAUSED your dog's STRESS
INDUCED AUTO-IMMUNE DIS-EASE a.k.a. The
Puppy Wizard's Syndrome <{}: ~ ( >
> --
> Mike
> -Please remove 'safetycatch' from email address
> before firing off your reply-
Perhaps you should try some self induced copulation, mikey?
trigonometry1972@gmail.com |
Perhaps we have another Todd on our hands.
I've come to have my doubts about spaying. A birth control option
might be
healthier. The female dogs would be far less likely to be incontinent/
leaky
and not need other daily meds to combat it if they still have a decent
estrogen level
from their ovaries.
On the other hand a bitch in heat can bring the "guys" in from blocks
around so
avoiding that experience is important to me. Though these days I'd
assume
most of the "guys" are traveling light and hence uninterested.
Would DHEA improve female canine incontinence? Any opinions.
Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory
<trigonom...@gmail.com> wrote in message
news:076e7fe9-023a-4ff0...@m45g2000hsb.googlegroups.com...
On Aug 5, 10:31 am, "mlv" <mike.safetycatchvinc...@jet.co.uk> wrote:
> "Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory" wrote:
>
> >> Welcome to The Sincerely Incredibly Freakin
> >> Insanely Simply...
>
> >> <stanch verbal diarrhoea>
Seems mlv got hisself EMBARRASSED <{}: ~ ( >
>> Unfortunately, any useful information that may have been
>> contained in your post was rendered inconspicuous by the
>> seemingly pointless verbosity.
Too much SCIENCE, eh?
NO PROBLEMO~!
It wasn't intended for ignorameHOWESES to read <{}: ~ ( >
>> Mike
>> -Please remove 'safetycatch' from email
>> address before firing off your reply-
Oh, an perhaps mike will READ THE ARCHIVES
pryor to postin ignorameHOWES questions <{}: ~ ( >
> Perhaps we have another Todd on our hands.
I don't remember Todd <{}: ~ ( >
> I've come to have my doubts about spaying.
AND vaccinations?
Ask your vet if HE'S lyin or if the RESEARCH is LYIN <{}: ~ ) >
> A birth control option might be healthier.
I see no need for birth controll in dogs who are apupriately
MANAGED an TRAINED to stay in their own terrortory.
> The female dogs would be far less likely to be incontinent/
> leaky and not need other daily meds to combat it if they still
> have a decent estrogen level from their ovaries.
Yeah. Female incontinence approaches 40% and "requires"
life-long DRUG THERAPY you can BUY from your
veterinary malpracticioner <{}: ~ ( >
> On the other hand a bitch in heat can bring the "guys"
> in from blocks around so avoiding that experience is
> important to me.
Your bitches will ward off any males they're not pals with.
> Though these days I'd assume most of the "guys"
> are traveling light and hence uninterested.
Between THAT and leash laws you'd think we'd have
NO overpupulation / euthanasia problems??
> Would DHEA improve female canine incontinence?
PROBABLY would heelp ALOT~!
> Any opinions.
Of curse I've never had a spay / neuter incontinent dog but
there's probably LOTS of other natural treatments for it.
ANY QUESTIONS, People?
INDEEDY.
The Sincerely Incredibly Freakin Insanely Simply
A-M-A-Z-I-N-G
M-A-J-E-S-T-I-C
G-R-A-N-D M-A-S-T-E-R
Puppy, Child, Pussy, Birdy, Ferret, Goat, Monkey
SpHOWES And Horsey Wizard <{) ;~ ) >
HOWE MAY I SERVE YOU <{}; ~ ) >
Sincerely,
Jerry Howe,
Director of Research,
Human And Animal Behavior
Forensic Sciences Research Laboratory,
BIOSOUND Scientific,
Director of Training,
Wits' End Dog Training
1611 24th St
Orlando, FL 32805
Phone: 1-407-425-5092 (Call ANY TIME)
http://www.freewebs.com/thesimplyamazingpuppywizard
E-mail:
Human_And_Animal_Behavior_Forensic_Sciences_Research_Laboratory
@HotMail.Com
unsurrea...@yahoo.com
"Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory"
<Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laborat...@HotMail.Com>
wrote:
> HOWEDY mlv,
>
> "mlv" <mike.safetycatchvinc...@jet.co.uk> wrote in message
>
> news:g7a2pg$gor$1...@north.jnrs.ja.net...
>
> > "Human_And_Animal_Behaviour_Forensic_Sciences_Research_Laboratory" wrote:
>
> >> Welcome to The Sincerely Incredibly Freakin
> >> Insanely Simply...
>
> >> <stanch verbal diarrhoea>
>
> That's KINDLY of you, mike. Your fellHOWE dog lovers here
> FEAR an HATE IT when people QUOTE EVIDENCE of lies
> insanity mutilation and abuse from The Sincerely Incredibly
> Freakin Insanely Simply Amazing, Majestic Grand Master Puppy,
> Child, Pussy, Birdy, Goat, Ferret, Monkey, SpHOWES, And Horsey
> Wizard's 100% CONSISTENTLY NEARLY INSTANTLY
> SUCCESSFUL FREE WWW Wits' End Training Method
> Manual Forums And Human And Animal Behavior Forensic
> Sciences Research Laboratory Archives <{}: ~ ) >
Yet no one fears quoting your lies. Is that strange, AssHowey?
>
> > Unfortunately, any useful information that may have been contained in your
> > post was rendered inconspicuous by the seemingly pointless verbosity.
>
> You mean that you're EMBARRASSED ASHAMED an
> HUMILIATED to realize that YOU and your veterinary
> malpracticioner have CAUSED your dog's STRESS
> INDUCED AUTO-IMMUNE DIS-EASE a.k.a. The
> Puppy Wizard's Syndrome <{}: ~ ( >
Gee. This is getting old, AssHowey. No one is ashamed or embarrassed
or humiliated by anything you've ever said. People are only
embarrassed FOR you seeing you are such a moron. Oh, here we go again
with "The Puppy Wizard's Syndrome." Ya. This is old and boring
already - try something different. Can't you come up with some
original material??? THAT is embarrassing - for you. Although I DO
think it's a good thing you named a disease after you since you are a
walking (with feeble cane) disease, AssHowey...
caninev...@gmail.com
5
I think we might have the cure for canine vitiligo. Our female retriever came down with canine vitiligo about 4-to-5 months ago. The good news is that she is just about CURED.
Here is what we did: Breeder has us start her on fish oil and granulated kelp, our vet put her on tritop cortisone creme and told us to take her to a canine dermatologist, So, we took her to UC Davis, a veterinary university in California. They had us put her on vitamin C and (very important) B vitamins that ALSO contain Intrinsic Factor, which is a dietary protein that aids in the absorption of b-vitamins. The very special intrinsic factor B-vitamins are manufactured and sold by Wonder Laboratories, and are called TrinFac B Intrinsic Factor. She has been on the Trinfac B and the vitamin C for about two months and her vitiligo is about 3/4 cured. I am optomistic, in another 2-months, it will be just about completely gone.
To put it all together for you, here is what we do:
Once a day:
1/2 tsp granulated kelp
1/2 tsp Norweigian cod liver oil
2 tablets Mega Red krill oil
Twice a day:
one in the morning and one in the evening evening, one tablet 500 mg vitamin C (two tablets per day)
3 times a week:
1 tablet TrinFac B (Mon Wed Fri)
1 tablet Solaray Zinc and Copper (Tues Thurs Sat)
Best wishes - I hope this helps you dog as it has helped ours. TO find the TrinFac, Google : Wonder Laboratories TrinFac B Intrinsic Factor. A bottle of 100 or 120 capsules costs about $15 US.