A Report From the Front
Positive, life-saving news from the trenches that’s going unreported by
those fearful of ending the lockdown.
George Parry by GEORGE PARRY
May 1, 2020, 12:07 AM
Ever since President Trump expressed optimism about the use of
hydroxychloroquine to treat COVID-19, the mere mention of that drug can
elicit instantaneous, strident, and finger-wagging condemnation by the
mainstream media and all those who are pulling for the pandemic to lay
waste to the economy and pave the way for a fundamental progressive
transformation of America. Despite its use by health-care providers
across the country and around the world to successfully treat COVID-19,
you will be mocked as either a fool or a snake oil salesman if you
approvingly utter the word “hydroxychloroquine” or even express hope
that it can be used to save lives. The word is simply not to be
tolerated in polite, progressive society.
Well, it appears that the list of forbidden words is about to get
longer. The new additions include “corticosteroids” and
“Methylprednisolone.”
What do these widely available and relatively inexpensive drugs with
known safety profiles have in common with hydroxychloroquine? Leading
physicians are using them in addition to hydroxychloroquine to
successfully treat COVID-19. And they are doing so without waiting two
or three years for the results of randomized clinical trials.
On April 6, 2020, the aptly named “Front Line COVID-19 Critical Care
Consortium” issued a bulletin urging the “immediate adoption of [an]
early intervention protocol to prevent mortality and reduce the use of
ventilators from COVID-19 disease.” The consortium consists of leading
critical care specialists from the University of Wisconsin School of
Medicine & Public Health, the University of Texas Health Science
Center, the University of Tennessee Health Science Center, Manhattan’s
Lenox Hill Hospital, the Eastern Virginia Medical School, and other
equally distinguished medical schools and centers.
Based on the available research and “their decades-long professional
experiences in Intensive Care Units around the country,” these experts
“strongly urge fellow physicians to immediately adopt a change in
strategy by delivering powerful [anti-inflammatory] therapies earlier
in the [COVID-19] disease course, prior to admission to the ICU or the
need for a mechanical ventilator.”
COVID-19 is caused by the SARS-CoV-2 virus. So, is this new drug
strategy calculated to eradicate the virus or reduce the patient’s
viral load? Not at all, but, as these experts explain, that is quite
beside the point.
One of the consortium members is Dr. Pierre Kory, the Medical Director
of the Trauma and Life Support Center and Chief of the Critical Care
Service at the University of Wisconsin in Madison. In the bulletin, he
explains that “it is the severe inflammation sparked by the
Coronavirus, not the virus itself, that kills patients. Inflammation
causes a new variety of Acute Respiratory Distress Syndrome (ARDS),
which damages the lungs.”
As spelled out in the consortium’s bulletin, the key to the new
treatment strategy is the early and prompt use of hydroxychloroquine
(which is also prescribed to reduce inflammation in lupus and
rheumatoid arthritis patients) and/or corticosteroids such as
Methylprednisolone to reduce the inflammation caused by the
coronavirus.
On April 20, 2020, Dr. Paul Marik, Chief of Pulmonary and Critical Care
Medicine at the Eastern Virginia Medical School, published a Critical
Care COVID-19 Management Protocol based on the consortium’s findings.
In the protocol, he states the following:
Scientific Rational[e] for Treatment Protocol
Three core pathologic processes lead to multi-organ failure and death
in COVID-19:
Hyper-inflammation (“Cytokine storm”) – a dysregulated immune system
whose cells infiltrate and damage multiple organs, namely the lungs,
kidneys, and heart. It is now widely accepted that SARS-CoV-2 causes
aberrant T lymphocyte activation resulting in a “cytokine storm.”
Hyper-coagulability (increased clotting) – the dysregulated immune
system damages the endothelium and activates blood clotting, causing
the formation of micro and macro blood clots. These blood clots impair
blood flow.
Severe Hypoxemia (low blood oxygen levels) – lung inflammation caused
by the cytokine storm, together with microthrombosis in the pulmonary
circulation severely impairs oxygen absorption resulting in oxygenation
failure.
The above pathologies are not novel, although the combined severity in
COVID-19 disease is considerable. Our long-standing and more recent
experiences show consistently successful treatment if traditional
therapeutic principles of early and aggressive intervention is
achieved, before the onset of advanced organ failure. It is our
collective opinion that the historically high levels of morbidity and
mortality from COVID-19 is due to a single factor: the widespread and
inappropriate reluctance amongst intensivists [critical care
physicians] to employ anti-inflammatory and anticoagulant treatments
[blood thinners], including corticosteroid therapy early in the course
of a patient’s hospitalization. It is essential to recognize that it is
not the virus that is killing the patient, rather it is the patient’s
overactive immune system. The flames of the “cytokine fire” are out of
control and need to be extinguished. Providing supportive care (with
ventilators that themselves stoke the fire) and waiting for the
cytokine fire to burn itself out simply does not work… this approach
has FAILED and has led to the death of tens of thousands of patients.
(Emphasis added.)
Similarly, consortium member Dr. Umberto Meduri, Professor of Medicine
at the University of Tennessee Health Science Center, advises that
“There is no justification based on available evidence and professional
ethics to categorically deny the use of corticosteroid
[anti-inflammatory] treatment in the severe life-threatening ‘cytokine
storm’ associated with COVID-19. Misinformation about the only
anti-inflammatory treatment available for this ‘cytokine storm’ has
resulted in COVID-19 patients dying from massive inflammation without
receiving an effective and safe anti-inflammatory treatment. Mortality
for ventilating patients is 50% — unacceptable.”
And Dr. Keith Berkowitz, a New York internist, adds, “Given the dire
circumstances in New York State, with almost 122,000 confirmed cases of
COVID-19 and 4,159 deaths, it is imperative that every hospital
immediately adopt this safe, low-cost and highly effective treatment
protocol, but they must implement it BEFORE the ICU, not after they
reach the ICU because, in this disease, the organ damage tends to be so
severe that patients rarely recover at that point.” (Emphasis added.)
Obviously, these findings and the announcement of this new treatment
protocol are great news for all of us who want lives to be saved and to
see an end to the massively destructive lockdown of our nation. After
all, isn’t the existence of an effective, widely available, scalable
treatment with a known safety profile for COVID-19 a powerful argument
for reopening America and ending government’s ongoing destruction of
our lives, livelihoods, and the economy?
Of course it is, which is why you will never hear about these findings
or strategy from the mainstream media and their progressive allies, who
have a stake in prolonging the lockdown. Just as they have mocked
hydroxychloroquine and banned any favorable mention of its use, you can
anticipate that news of the consortium’s protocol or any other
successful treatment available in the here and now — and arrived at
without a lengthy delay for randomized clinical trials — will go down
Orwell’s “memory hole.” Not only would such good news run counter to
the prevailing progressive orthodoxy that the only responsible,
“science-based” course is to keep America locked down, it would also
vindicate President Trump’s expressed optimism about hydroxychloroquine
— a clearly unacceptable outcome for our progressive betters.
But here’s a question: why weren’t physicians from the very onset of
the pandemic using this or a similar strategy to treat the inflammation
caused by SARS-CoV-2? As stated in Dr. Marik’s treatment protocol, the
consortium provides this disturbing answer:
The systematic failure of critical care systems to adopt corticosteroid
[anti-inflammatory] therapy resulted from the published recommendations
against corticosteroids use by the World Health Organization (WHO), the
Centers for Disease Control and Prevention (CDC), and the American
Thoracic Society (ATS) amongst others. A very recent publication by the
Society of Critical Care Medicine and authored [by] one of the members
of our group (UM), identified the errors made by these organizations in
their analyses of corticosteroid studies based on the findings of the
SARS and H1N1 pandemics. Their erroneous recommendation to avoid
corticosteroids in the treatment of COVID-19 has led to the development
of myriad organ failures which have overwhelmed critical care systems
across the world.
Our treatment protocol targeting these key pathologies has achieved
near uniform success, if begun within 6 hours of a COVID19 patient
presenting with shortness of breath or needing ≥ 4L/min of oxygen. If
such early initiation of treatment could be systematically achieved,
the need for mechanical ventilators and ICU beds will decrease
dramatically. [Emphasis added.]
Got that? The World Health Organization, which authoritatively told us
that there was no human-to-human transmission of the virus and which
bitterly condemned President Trump’s China travel ban, and the CDC,
which wasted precious weeks using the wrong test for SARS-CoV-2,
recommended against using anti-inflammatory drugs to treat COVID-19.
This failure and misinformation by these taxpayer-funded organizations
are as infuriating as the Food and Drug Administration’s recent warning
about hydroxychloroquine possibly causing irregular heartbeat in
COVID-19 patients even though the FDA provides no similar warning for
the millions of persons who take it for malarial prophylaxis or as an
anti-inflammatory in the treatment of lupus and rheumatoid arthritis.
Finally, are you ready for some real irony? Remember those tens of
thousands of ventilators that Gov. Andrew Cuomo demanded that the
federal government provide? The consortium strongly recommends that
they be used only as an absolute last resort. Why? As Dr. Marik points
out, “early intubation” will “cause the disease you are trying to
prevent, i.e., ARDS [Acute Respiratory Distress Syndrome].” Ventilators
not only cause mechanical injury to the patient’s lungs and “stoke the
cytokine fire,” but Dr. Howard Kornfeld, President of the Pharmacology
Policy Institute, adds that “This protocol will not only save patients
lives, it will also lessen the danger to the doctors and nurses who
treat them by decreasing the need for mechanical ventilators.” In
short, in addition to harming the patient, use of a ventilator also
increases the medical staff’s risk of infection.
All that you have just read is the work product of highly qualified
experts who are on the front lines every day successfully treating
COVID-19. They are not living in ivory towers and pontificating from on
high about the need for randomized clinical trials and the production
of vaccines that are years away from being developed — if they ever
will be. Theirs is a report from the trenches, and it is all positive,
good news. It is also comprised of vital information that must be made
public so that, hopefully, it will inform the debate as to when, if
ever, America may be liberated from its suicidal, government-imposed
imprisonment. Since we can’t count on the mainstream media to report
these findings fully or fairly, I urge you to copy the consortium’s
linked documents and share them with one and all, including your
doctors.
I also urge you to have copies available to take with you to the
hospital if, God forbid, you become infected. Keep in mind that the
consortium strongly recommends that the administration of the
hydroxychloroquine, Methylprednisolone, or whatever corticosteroid
should promptly begin in the emergency room and continue throughout
hospitalization. As noted by the consortium, there is resistance to
using its anti-inflammatory strategy, and, for that reason, you must be
ready to be your own best patient advocate.
So, as we used to say in the Boy Scouts, “Be prepared” by having
printed copies of the consortium’s documents readily available. The
life you save may be your own.
George Parry is a former federal and state prosecutor. He blogs at
knowledgeisgood.net and may be reached by email at
kig...@gmail.com.
https://spectator.org/a-report-from-the-front/