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Levamisole EPM????

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Dean & Sue Brickell

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Mar 6, 2000, 3:00:00 AM3/6/00
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Has anyone used levamisole for epm? How did you use it and what were your
results?

OKSTABLES

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Mar 7, 2000, 3:00:00 AM3/7/00
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>Subject: Levamisole EPM????
>From: "Dean & Sue Brickell"

>Has anyone used levamisole for epm?

I have only used Levamisole as a broad spectrum anthelmintic, effective against
nematodes in cows, pigs and sheep. Would love to know if it has been used in
EPM cases. Thanks Jay

C.M.Newell

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Mar 7, 2000, 3:00:00 AM3/7/00
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It seems to have *some* immunomodulating properties. There are
sometimes side effects with its use in horses, I believe, which is why
it isn't used as an anthelmintic in the species.

CMNewell, DVM
self-proclaimed vet
Surgeon General of the Bogbash Party

OKSTABLES

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Mar 7, 2000, 3:00:00 AM3/7/00
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>Subject: Re: Levamisole EPM????
>From: res...@deyr.ultranet.com (C.M.Newell)

>There are
>sometimes side effects with its use in horses, I believe, which is why
>it isn't used as an anthelmintic in the species.

I have also seen side effects with it's use in cattle, thanks for the info. The
treatments for EPM seem to be improving, as are the tests. Jay

D.Melvina Harris

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Mar 7, 2000, 3:00:00 AM3/7/00
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Dean & Sue Brickell wrote:
> Has anyone used levamisole for epm? How did you use it and what were your
> results?

Rap has been on levamisole every other week since going off of EPM meds
last April. I first heard about it from Susan Brady, who I see has
replied to your post. My vet got dosage info from Dr.MacKay at U of FL
vet school who used levamisole with the regular EPM meds.

The blood tests done at the time Rap was first examined/tested for EPM
showed he had low red & white cell counts, so he was also put on RedCell
& vitamin E with the EPM meds & then levamisole. After he recovered
from the EPM, he needed throat surgery in June. Blood tests at that
time showed his red & white cells were up to normal ranges, which we
attribute to the Red Cell & the levamisole.

Aside from EPM, he also has sarcoids which are also indication of a poor
immune system. While still on the levamisole, he had a flare up of the
sarcoids last Fall, and a few weeks ago showed signs of the EPM
relapsing, which is being treated with Baycox this time. I requested
new blood tests to check the current status of his red & white blood
cells.

So, it appears levamisole does boost the immune system, but, at least in
Rap's case, it's not a cure all. It seems to be good as a supplement to
other treatments.

So, have I muddied the waters on this issue enough?
--Melvina--

susan brady

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Mar 8, 2000, 3:00:00 AM3/8/00
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In January 1998, my horse was diagnosed with EPM and my two vets
recommended Levamisole as the sole therapy. My horse suffered no side
effects from the Levamisole and he has no residual EPM symptoms. He is
showing third level without a hitch.

Susan

OKSTABLES

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Mar 8, 2000, 3:00:00 AM3/8/00
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>Subject: Re: Levamisole EPM????
>From: "D.Melvina Harris" melv...@ix.netcom.com

>So, have I muddied the waters on this issue enough?
> --Melvina--
>

No this is great, do you think Dr. MacKay would have any information that I
could get to on the web? I would love to learn more. Thanks Jay

L7 Ranch

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Mar 14, 2000, 3:00:00 AM3/14/00
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OKSTABLES <okst...@aol.com> wrote in message > No this is great, do you

think Dr. MacKay would have any information that I
> could get to on the web? I would love to learn more. Thanks Jay

Levamisol or Levasol as some folks refer to it, is sheep wormer.
Injected, and used on horses, it has been purported to increase
immunity. I couple of years ago, a big undertaking went on
as the med community decided to use it in cancer research
for people. I never heard whether or not they decided it was
an effective treatment. But a vet I know and respect suggested
it for a mare that was coughing and I gave her several injections
of it.

Sue in Simla

OKSTABLES

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Mar 15, 2000, 3:00:00 AM3/15/00
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>Subject: Re: Levamisole EPM????
>From: "L7 Ranch" l7r...@earthlink.net

>Levamisol or Levasol as some folks refer to it, is sheep wormer.
>Injected, and used on horses, it has been purported to increase
>immunity.

Sue, we do not use as much Levamisol on Cattle as we used to, there are some
side effects that cattle can have.

>But a vet I know and respect suggested
>it for a mare that was coughing and I gave her several injections
>of it.

How did it work? Any side effects? Thanks for the info, it is great of you to
take the time to share. Jay

L7 Ranch

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Mar 15, 2000, 3:00:00 AM3/15/00
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OKSTABLES <okst...@aol.com> wrote in message

> Sue, we do not use as much Levamisol on Cattle as we used to, there are


some
> side effects that cattle can have.

I said it was =sheep= wormer. I don't use it on cattle. Where did you
get that?

> How did it work? Any side effects? Thanks for the info, it is great of
you to
> take the time to share. Jay

No side effects. And it didn't work. What did work was taking her
off any and all hay and feeding her pellets instead. She was coughing
on the hay even though it was very clean. We tried the Levasol injections
and then we waited. She continued to cough, though the congestion
did clear up. However, since we didn't want to press her condition
into COPD type thing, we just switched her feeding regimine. After we
did that, the coughing stopped.

Sue in Simla

OKSTABLES

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Mar 16, 2000, 3:00:00 AM3/16/00
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>Subject: Re: Levamisole EPM????
>From: "L7 Ranch" l7r...@earthlink.net

>I said it was =sheep= wormer. I don't use it on cattle. Where did you
>get that?
>
>

It was used not only on sheep and cattle but also pigs, it does however have a
narrow margin of safety. Weight estimates need to be correct.

Suzan

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Mar 16, 2000, 3:00:00 AM3/16/00
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Sue writes:....

>But a vet I know and respect suggested it for a >mare that was coughing
and I gave her >several injections of it.

And what was the outcome, Sue?

Suzan


L7 Ranch

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Mar 17, 2000, 3:00:00 AM3/17/00
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> And what was the outcome, Sue?
>
> Suzan

She quit coughing as much, but we ended up putting her on pellets
at the vet's advice. She didn't have COPD, and we didn't want her
to develop it either. She had no temp, nothing to indicate that she
was fighting a virus, vet said that doing allergy tests woudl be expensive,
so we gave the injections, waited, and then switched her feed.
All in all the whole regimine worked. If she was harboring a low
level viral infection it cleared up we think, though as she was never
really symptomatic except for the coughing it was hard to say.

The injections didn't appear to hurt her at all. What I find interesting,
is that most vets are just now starting to prescribe Levasol injections.
The vet that had me give them, prescribed it to us oh, about 10 years
ago. This guy has always been well ahead of the game in a lot of ways.

Sue in Simla

C.M.Newell

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Mar 17, 2000, 3:00:00 AM3/17/00
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On Fri, 17 Mar 2000 15:27:25 GMT, "L7 Ranch" <l7r...@earthlink.net>
wrote:


>... What I find interesting,


>is that most vets are just now starting to prescribe Levasol injections.
>The vet that had me give them, prescribed it to us oh, about 10 years
>ago. This guy has always been well ahead of the game in a lot of ways.
>

Maybe it's cyclical, because I first heard of using it for
chronic respiratory stuff in horses well over 10 years ago.

OKSTABLES

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Mar 18, 2000, 3:00:00 AM3/18/00
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>Subject: Re: Levamisole EPM????
>From: "L7 Ranch"

> What I find interesting,


>is that most vets are just now starting to prescribe Levasol injections.
>The vet that had me give them, prescribed it to us oh, about 10 years
>ago. This guy has always been well ahead of the game in a lot of ways.
>

>Sue in Simla
>

> She didn't have COPD,

Sue, I wonder if anyone has tried this on horses with COPD?? Do you know of an
cases? As always, thanks for the info. Jay

L7 Ranch

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Mar 18, 2000, 3:00:00 AM3/18/00
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OKSTABLES <okst...@aol.com> wrote in message

> Sue, I wonder if anyone has tried this on horses with COPD?? Do you know


of an
> cases? As always, thanks for the info. Jay

I'm not aware of any, maybe Doc Newell is aware of something?

Sue in Simla

OKSTABLES

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Mar 18, 2000, 3:00:00 AM3/18/00
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>Subject: Re: Levamisole EPM???? Doc Newell
>From: res...@deyr.ultranet.com (C.M.Newell)
>Date: 03/18/2000 12:04 PM Central Standard Time

>That was the initial use of it in horses that I was familiar
>with.

>Thoses I know of that were on it for COPD were reported by the
>owners as nost being significantly better.

Can be a very tragic disease. We have gotten better results with Clenbuterol
lately. Too bad the AHSA dosen't make it legal. Thanks for the info, as always
trying to keep old brain cells awake. Jay

L7 Ranch

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Mar 19, 2000, 3:00:00 AM3/19/00
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OKSTABLES <okst...@aol.com> wrote in message
>
> Can be a very tragic disease. We have gotten better results with
Clenbuterol
> lately.

Clenbuterol is a bronchiodilator... BIG difference, as opposed
to giving shots to boost the immune system....

> Too bad the AHSA dosen't make it legal.

It is, and it isn't. It boosts the heart rate, and can act as a stimulant
for that reason. To some degree, it could provide for an unfair
advantage.

> Thanks for the info, as always
> trying to keep old brain cells awake.

Never hurts :-)

Sue in Simla

OKSTABLES

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Mar 22, 2000, 3:00:00 AM3/22/00
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>Subject: Re: Levamisole EPM???? Doc Newell
>From: "L7 Ranch" l7r...@earthlink.net

>Clenbuterol is a bronchiodilator... BIG difference, as opposed
>to giving shots to boost the immune system....

Was not grouping them in the same class, only as another treatment for COPD,
better than Albuterol. The side effects would not be of great benefit to a
hunter, although some people will try anything that they think will give them
an "advantage". There is a barn that has been fined twice now for cocaine! I
can't imagine sitting on a 1000Lb horse that is "high" and trying to jump
around a course. I would imagine that there are those that would give
Clenbuterol to their jumpers to perhaps get them a bit more "up", but I work
hard to make sure all my jumpers are as soft and quiet as they can be.

L7 Ranch

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Mar 22, 2000, 3:00:00 AM3/22/00
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OKSTABLES <okst...@aol.com> wrote in message
> Was not grouping them in the same class, only as another treatment for
COPD,
> better than Albuterol.

Oh, ok. Sorry 'bout that :-)

[snip]


> but I work
> hard to make sure all my jumpers are as soft and quiet as they can be.

You should get an award then. There are =way= too many of the other types
out there competing, IMO :-)

Sue in Simla

OKSTABLES

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Mar 23, 2000, 3:00:00 AM3/23/00
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>Subject: Re: Levamisole EPM???? Doc Newell
>From: "L7 Ranch"

>There are =way= too many of the other types


>out there competing, IMO :-)
>
>Sue in Simla
>

Sue, so many people feel if it is too "hot" to be a hunter, then it is a
jumper, (or event horse). It is too bad, they just end up with crazy jumpers,
much more stressful that a hot hunter. Although I can't always pick and choose
the horses that are here for training or lessons, I would much rather have one
that is soft, and quiet. I have found, you can always make one go faster, but
it is damm hard to make one go slower. Most jumpers don't go fast at all, they
are prompt, no senic tours, and are very well balanced. The "fast" ones (read
nuts) may win a class or two when they are lucky enough to leave the jumps up!
But the consistant ones walk into the ring, and leave the ring on a loose rein,
at a walk. Although they may stop for a pat, or in my sons case the bite of the
treat he has in his pocket. Sorry off topic, I know, but it is one of my pet
peeves, if it is too crazed to be a hunter, I dang (Okie Speak) sure don't want
to ride it around 4'6".

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