Unfortunately - yes, although it's unusual to blow anything up if it's only been miswired briefly.
I would suggest
- Unplug all the cards
- Inspect the backplane soldering and look for dry joints and cracks. The RC2014 backplane takes a lot of force when removing and adding cards and is nowhere near thick enough to be properly robust. You may have a problem with the backplane needing a resolder that is everything to do with a bad joint and nothing to do with the misaligned cards. If you have a different backplane try it.
- Put back the clock card, check the power and clock with a voltage meter/frequency meter or similar
- Pull the ROM and test it by reading it back in a programmer, and if need be rewriting it
- Some programmers can also test RAM
- Stick the CPU card in and see if there is activity on the address/data lines (it'll be executing nonsense but it'll be executing so you should see activity on M1, RD, WR, MREQ and A0-A15). Also check voltages.
- Stick the RAM/ROM card back in and check voltages. You could also burn "IN A,(FF), JP 0 into the start of the ROM and see if the CPU lines behave as you'd expect (you'll get some activity at other addresses due to the built in DRAM refresh) but should see lots of IRQ activity and so on
- Ditto the serial and see if it's now alive.
Otherwise starting with the highest density components is my rule of thumb - the size of the features has a lot to do with how destructible the chip is. Apart from the components on the misaligned card I would start with the CPU if the clock is good and nothing seems to work.
Alan