GTR+gamma

[Ketaki Hardikar]

What is GTR? why is it used? advantages? what is gamma? why is it used? 

[Grimm]

Hi Hardika,

GTR stands for general time-reversible, it's the most general molecular substitution model. With the gamma parameter, we model per-site variance of the substitution probablities.

For such very basic questions, Wikipedia is not the worst place to start:

Substitution model—https://en.wikipedia.org/wiki/Substitution_model,

Gamma distribution–https://en.wikipedia.org/wiki/Gamma_distribution

If very new to phylogenetics, you may want to give the free-available chapter 16 of Genomes: Molecular Phylogenetics, a read.

https://www.ncbi.nlm.nih.gov/books/NBK21122/

And, to dwelve deeper into the topic and current day use, this open-access book:

Phylogenetics in the Genomic Era

https://hal.archives-ouvertes.fr/PGE

Cheers, G

[Harsh Kashyap]

Please check for GTR in Detail