Hi Surge,
First and foremost Quine is designed to support TiddlyWiki standalone .html files. Its primary job is to load, present and save TiddlyWiki .html files. It does NOT automatically save individual tiddlers. It does NOT run a TiddlyWiki server. It is perhaps best to think of Quine as giving you the equivalent of TiddlyWiki .html files in a browser with save capabilities. I wrote Quine because this was/is not possible in Safari etc on iOS.
To do what you want you could try the following scenario:
1. Create a folder in iCloud containing an empty.html plus all of your tiddler files
2. Open the empty.html in Quine
3. Import all of your tiddler files using the TiddlyWiki import tool
4. Work with your wiki as needed
5. Save as needed
6. Export al of your tiddlers using TiddlyWiki export tool when you want to send the work back to your nodeJS environment
7. iCloud will handle the tiddler file sync
Meanwhile, I have a long standing experimental "filesystem saver" for Quine, which implements the TiddlyWiki "filesystem-saver" - writing out tiddler files as they change in the wiki. It's been on-hold as I've not seen huge demand or managed to get clear on the right overall use-case. Right now I'm in the middle of writing Quine 3, but DO want to find a good way to support your kind of scenario if there is demand. I'm happy to revisit the experimental filesystem-saver project as soon as I get Quine 3 completed - but can't promise anything yet.
If you try the suggestion above please let me know how it goes.
Chris.