Installed Qubes with no (noticable) issues.
Attempted EFI boot fails -- I disabled the quiet flags and it seems to hang after loading Linux (the last line displayed is something relating to EFI variables, iirc)
Legacy boot works fine. Tested various VMs, seems to be working well. Networking works OOB, audio works, etc.
TPM is installed on the board and I was able to use it successfully. Tested AEM, seems to work thus far.
Only real annoyance is that the RF kill key doesn't seem to work (at least when using XFCE, haven't tried KDE).