Fixed :-)
grub.cfg corrupted. Missing two lines :
echo 'Loading initial ramdisk ...'
module --nounzip /initramfs-4.14. 74-1.pvops.qubes.x86_64.img
I found a backup of the grub.cfg file in user's home directory (dated Sept. 26 2018). Fortunately I make backups.
Reboot with an older kernel version and :
sudo dracut /boot/initramfs-4.14.74-1.pvops.qubes.x86_64.img 4.14. 74-1.pvops.qubes.x86_64
sudo grub2-mkconfig -o /boot/grub2/grub.cfg
It is now fully operationnal.