no ps2 ports and only one usb controller, so no usbvm. dont use this if malicious usb devices are in your threat model.
This is brand new hardware, so it may have trouble with qubes 3.2.
if your going to also run windows on this, i suggest putting qubes on the external one. that way, when you boot windows, it wont have a chance to mess with your qubes drive. or even better, swapping the drives so you dont risk accidentally booting windows with your qubes disk still in.
If your photoshop and illustrator files are not too demanding, you can run windows in qubes and save yourself that effort. ive never tried it, only seen a coworker do it.