NUC's are promising. 64GB memory with 1TB NVMe is
acceptable for a Qubes installation and takes up zero space.
Got 800x600 with the 4.19 kernel. no wifi. Upgraded kernel to 5.5.13-1 and got my 4K monitor working. no wifi. wifi device flapping for a few minutes, then stop. Hoping for some upgrades at some point.
Runs current-testing repo.
I tried the predecessor NUC8i7 and it made a lot of noise every time it had to do more than showing the plain desktop.I'm back to a proper desktop PC where fans only start getting noisy when a job runs on multiple cores full load for several minutes.
I recently moved to Xubuntu on this device, since QubesOS suddenly would not boot anymore. Just hung and my 4K support dissapeared suddenly a few weeks prior to that.
I am sorry it's such a hassle. Kali, Ubuntu, etc. has no issues with wireless so it seems to be Qubes specific.
Good luck. You will need it.