To be honest, it's doesn't sound like you have much of hope unless you can get the venue to cooperate. Just 'hacking in' isn't going to work, and quite honestly is a bad plan ethically. They have reasons for locking out their system and if they don't want you in there, all your going to do is make them mad and at best, you'll wind up out of a job. Stick to being open and honest. I don't mean to imply you aren't, I'm just making sure that's said here before I start answering questions.
You imply they are at least willing to talk when you say they'll let you plug in a second interface. You'll need to get them to go further if you want this to work. This isn't something you're going to be able to do without their help at least. If nothing else, they have to let you connect to their Mac and tell you what the settings are.
> They already have a midi in on their mac rig but it's tied up? It goes to their light board but it is not accessible.
The MIDI IN comes from the light board? That would mean the light board is talking to the Mac and triggering cues? You were describing the other way around - the Mac was triggering the light board. That would be the MIDI OUT on the Mac. Of course it's possible it goes both ways, but that makes my brain hurt... :-)
> They are willing to let you add a second USB to midi interface? YES
> Are they willing to let you dictate what settings you need setup on the
> lighting mac? maybe :-/
> Are they willing to let you install a driver if necessary for the USB to
> Midi device you might add? Probably no.
Unless the answers to all three above questions is a 'yes' then you can't use MIDI. Plugging in a MIDI interface may work so long as it's the same make/model as the existing one and uses the same driver. However, if you can't set MIDI up on their QLab, then you can't trigger it. It may be that it's already set up (if their light board is triggering it) in which case you would just need to use those settings in your MSC commands.
> Midi seems like a much better option. Maybe even over a hardwired ethernet
> connection.
>
> I know people are doing this but I'll have to let them step in here.
MIDI over Ethernet isn't tough provided you can install ipMIDI on the machine... and there we go needing to install something on their machine again :-(