We unfortunately don't have a definitive answer for you. There isn't any new development on QIIME1, so macqiime has not been tested on Catalina.
Unless you have a very specific reason to continue using QIIME1, I would strongly suggest processing your data with QIIME2, which is under active development and has newer features, such as denoising for Illumina data:
https://qiime2.org/installation: