CFFI 1.5 has been released, soon after CFFI 1.4. The new feature is
*embedding*. Historically, CFFI allowed you to forget the CPython C
API when you're writing extension modules. Now it also supports the
use case of embedding Python inside another application. Moreover,
the CFFI solution works identically on any version of CPython, and
also on PyPy.
(The PyPy that supports this is not released yet, but you can try the
nightly binaries at http://buildbot.pypy.org/nightly/trunk/