In [20]: df
Out[20]:
0 1 2 3 4
0 0.852543 0.671119 0.186331 0.941615 0.436338
1 0.564321 0.013514 0.020539 0.606974 0.736674
2 0.811880 0.217941 0.083967 0.105470 0.552018
3 0.278145 0.854468 0.884766 0.281775 0.934472
4 0.728728 0.919129 0.301560 0.623416 0.554836
In [21]: df[0] == df.ix[0,0]
Out[21]:
0 True
1 False
2 False
3 False
4 False
In [19]: df[df[0] == df.ix[0,0]]
Out[19]:
0 1 2 3 4
0 0.852543 0.671119 0.186331 0.941615 0.436338
In [22]: df[0]
Out[22]:
0 0.852543
1 0.564321
2 0.811880
3 0.278145
4 0.728728
In [24]: df[df[0] == df.ix[0,0]] = 5
In [25]: df
Out[25]:
0 1 2 3 4
0 5 0.671119 0.186331 0.941615 0.436338
1 5 0.013514 0.020539 0.606974 0.736674
2 5 0.217941 0.083967 0.105470 0.552018
3 5 0.854468 0.884766 0.281775 0.934472
4 5 0.919129 0.301560 0.623416 0.554836