Pyclone error

[Tongwu Zhang]

Hello I am try to run cyclone with the following command. however, the program give me some some error information. Can you help to check and give us suggestion how to fix it? thanks. 

---- COMMAND EXECUTED: ---------------------------------------------------------

(  PyClone run_analysis_pipeline --in_files TSV/IGC-04-1189-T01.tsv --tumour_contents 0.81 --working_dir IGC-04-1189 --min_cluster_size 5 )

--------------------------------------------------------------------------------

Beginning analysis using:

1326 mutations

1 sample(s)

Iteration: 0

Number of clusters: 1326

DP concentration: 1.0

Beta-Binomial precision: 1000

Iteration: 100

Number of clusters: 13

DP concentration: 2.25980603666

Beta-Binomial precision: 1098.76634471

Iteration: 200

Number of clusters: 24

DP concentration: 6.09157495006

Beta-Binomial precision: 1177.02186319

Iteration: 300

Number of clusters: 10

DP concentration: 1.67108068625

Beta-Binomial precision: 1132.83444532

Iteration: 400

Number of clusters: 21

DP concentration: 2.58453315023

Beta-Binomial precision: 1023.50614333

Iteration: 500

Number of clusters: 12

DP concentration: 1.63723011768

Beta-Binomial precision: 1052.53123506

.........

........

Iteration: 9600

Number of clusters: 6

DP concentration: 1.04760056092

Beta-Binomial precision: 1125.41650522

Iteration: 9700

Number of clusters: 14

DP concentration: 3.18601530227

Beta-Binomial precision: 1212.35267071

Iteration: 9800

Number of clusters: 9

DP concentration: 1.92790582303

Beta-Binomial precision: 1173.29606229

Iteration: 9900

Number of clusters: 10

DP concentration: 1.81040444204

Beta-Binomial precision: 1059.07940048

QStandardPaths: XDG_RUNTIME_DIR not set, defaulting to '/scratch/zhangt8/runtime-zhangt8'

Cannot mix incompatible Qt library (version 0x50905) with this library (version 0x50906)

/spin1/swarm/zhangt8/gHRNMhKgHj/cmd.53: line 1: 16801 Aborted                 ( PyClone run_analysis_pipeline --in_files TSV/IGC-04-1189-T01.tsv --tumour_contents 0.81 --working

_dir IGC-04-1189 --min_cluster_size 5 )

Thanks so much., 

[Andrew]

There seems to be some library incompatibility issues. Try creating a new conda environment and doing a fresh install. It also looks like matplotlib is using the QT backend instead of AGG. This can cause issues. See this post about how to edit your matplotibrc and fix it https://matplotlib.org/faq/usage_faq.html#what-is-a-backend.