Trasylol Kidney Damage Side Effects
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Steve Fields
Mar 27, 2013, 10:00:06 PM3/27/13
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Steve Fields
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Article Title: Trasylol Kidney Damage Side Effects
Author: Steve Fields
Word Count: 534
Article URL: http://www.isnare.com/?aid=145935&ca=Legal
Format: 64cpl
Contact The Author: http://www.isnare.com/eta.php?aid=145935
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Bayer's Trasylol problems are growing following increasing reports of the drug's side effects. Trasylol has recently been linked to a higher risk of kidney damage, heart attack, and death in the five years following a patient undergoing bypass heart surgery. In 1993 Trasylol (Aprotinin) was approved by the Federal Drug Administration. Aprotinin is manufactured by Bayer under the brand name Trasylol. Over the past several years Trasylol sales continued to increase even though studies indicated serious Trasylol kidney damage side effects.
Most heart surgery patients don't know if they were given Trasylol during their open heart surgery. Many patients suffering from Trasylol kidney damage side effects don't know if they were given Trasylol during their surgery because the surgeon made the decision whether to administer the drug to stop excessive bleeding during surgery.
Trasylol affects the way in which blood clots. It is given to open heart surgery patients to prevent excessive bleeding side effects. Trasylol is mainly used during repeat coronary artery bypass surgery to reduce the amount of bleeding both during and after surgery. The drug has been in use for 13 years and a million patients have received it. One of the most serious complications for bypass surgery patients is excessive bleeding. Clotting medications such as Trasylol reduce the amount of blood transfusion needed during surgery. In 2006 The New England Journal of Medicine (NEJM) published a study that reported Trasylol problems with an increased risk of developing heart failure, kidney damage, myocardial infarction, and stroke in bypass heart surgery patients.
On September 21, 2006 the FDA's Cardiovascular and Renal Drug Advisory Committee met to evaluate current data regarding Trasylol side effects. On September 29, 2006, the FDA issued a public health advisory stating that it had new information that Bayer failed to disclose an earlier study that it had conducted involving 67,000 heart surgery patients. Preliminary review of this study suggested that Trasylol side effects included higher risks for stroke, congestive heart failure, kidney damage, and death. Bayer failed to disclose this study during the Advisory Committee on September 21, 2006.
Dr. Dennis Mangano, the lead author of the NEJM Trasylol side effects study, has noted that Trasylol problems occurred more frequently than those linked with the drug Vioxx. Dr. Mangano relates, "In fact our findings raise even more troubling concerns, for:
(1) aprotinin has been on the market for three times as long as Vioxx, yet few comprehensive safety studies have been conducted since approval;
(2) the life-threatening complications with aprotinin found here occurred far more frequently than those with Vioxx; and
(3) far less expensive generic alternatives to aprotinin which are equally effective in limiting bleeding have been available, but have been underused."
The observational study concluded, "Our findings raise serious concerns regarding the safety of an approved drug intended to limit blood loss in at-risk patients undergoing surgery." Mangano related his opinion regarding the ongoing use of Trasylol, stating "In good conscience, I could not administer (Trasylol) to this group of patients, especially given the availability of safer alternatives." Trasylol problems continue to be studied and the FDA is monitoring Trasylol kidney damage side effects and advising physicians to consider limiting the drug's use.
About The Author: Steve Fields http://www.injurygroup.com
Please use the HTML version of this article at:
http://www.isnare.com/html.php?aid=145935
*********************** ARTICLE END ***********************
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Message delivered directly to members of the group:
publish-the...@googlegroups.com
*****************************************************************
Please consider this free-reprint article written by:
Steve Fields
*****************************
IMPORTANT - Publication/Reprint Terms
- You have permission to publish this article electronically in free-only publications such as a website or an ezine as long as the bylines are included.
- You are not allowed to use this article for commercial purposes. The article should only be reprinted in a publicly accessible website and not in a members-only commercial site.
- You are not allowed to post/reprint this article in any sites/publications that contains or supports hate, violence, porn and warez or any indecent and illegal sites/publications.
- You are not allowed to use this article in UCE (Unsolicited Commercial Email) or SPAM. This article MUST be distributed in an opt-in email list only.
- If you distribute this article in an ezine or newsletter, we ask that you send a copy of the newsletter or ezine that contains the article to http://www.isnare.com/eta.php?aid=145935
- If you post this article in a website/forum/blog, ALL links MUST be set to hyperlinks and we ask that you send a copy of the URL where the article is posted to http://www.isnare.com/eta.php?aid=145935
- We request that you ask permission from the author if you want to publish this article in print.
The role of iSnare.com is only to distribute this article as part of its Article Distribution feature ( http://www.isnare.com/distribution.php ). iSnare.com does NOT own this article, please respect the author's copyright and this publication/reprint terms. If you do not agree to any of these terms, please do not reprint or publish this article.
*****************************
Article Title: Trasylol Kidney Damage Side Effects
Author: Steve Fields
Word Count: 534
Article URL: http://www.isnare.com/?aid=145935&ca=Legal
Format: 64cpl
Contact The Author: http://www.isnare.com/eta.php?aid=145935
Easy Publish Tool: http://www.isnare.com/html.php?aid=145935
*********************** ARTICLE START ***********************
Bayer's Trasylol problems are growing following increasing reports of the drug's side effects. Trasylol has recently been linked to a higher risk of kidney damage, heart attack, and death in the five years following a patient undergoing bypass heart surgery. In 1993 Trasylol (Aprotinin) was approved by the Federal Drug Administration. Aprotinin is manufactured by Bayer under the brand name Trasylol. Over the past several years Trasylol sales continued to increase even though studies indicated serious Trasylol kidney damage side effects.
Most heart surgery patients don't know if they were given Trasylol during their open heart surgery. Many patients suffering from Trasylol kidney damage side effects don't know if they were given Trasylol during their surgery because the surgeon made the decision whether to administer the drug to stop excessive bleeding during surgery.
Trasylol affects the way in which blood clots. It is given to open heart surgery patients to prevent excessive bleeding side effects. Trasylol is mainly used during repeat coronary artery bypass surgery to reduce the amount of bleeding both during and after surgery. The drug has been in use for 13 years and a million patients have received it. One of the most serious complications for bypass surgery patients is excessive bleeding. Clotting medications such as Trasylol reduce the amount of blood transfusion needed during surgery. In 2006 The New England Journal of Medicine (NEJM) published a study that reported Trasylol problems with an increased risk of developing heart failure, kidney damage, myocardial infarction, and stroke in bypass heart surgery patients.
On September 21, 2006 the FDA's Cardiovascular and Renal Drug Advisory Committee met to evaluate current data regarding Trasylol side effects. On September 29, 2006, the FDA issued a public health advisory stating that it had new information that Bayer failed to disclose an earlier study that it had conducted involving 67,000 heart surgery patients. Preliminary review of this study suggested that Trasylol side effects included higher risks for stroke, congestive heart failure, kidney damage, and death. Bayer failed to disclose this study during the Advisory Committee on September 21, 2006.
Dr. Dennis Mangano, the lead author of the NEJM Trasylol side effects study, has noted that Trasylol problems occurred more frequently than those linked with the drug Vioxx. Dr. Mangano relates, "In fact our findings raise even more troubling concerns, for:
(1) aprotinin has been on the market for three times as long as Vioxx, yet few comprehensive safety studies have been conducted since approval;
(2) the life-threatening complications with aprotinin found here occurred far more frequently than those with Vioxx; and
(3) far less expensive generic alternatives to aprotinin which are equally effective in limiting bleeding have been available, but have been underused."
The observational study concluded, "Our findings raise serious concerns regarding the safety of an approved drug intended to limit blood loss in at-risk patients undergoing surgery." Mangano related his opinion regarding the ongoing use of Trasylol, stating "In good conscience, I could not administer (Trasylol) to this group of patients, especially given the availability of safer alternatives." Trasylol problems continue to be studied and the FDA is monitoring Trasylol kidney damage side effects and advising physicians to consider limiting the drug's use.
About The Author: Steve Fields http://www.injurygroup.com
Please use the HTML version of this article at:
http://www.isnare.com/html.php?aid=145935
*********************** ARTICLE END ***********************
- To distribute your articles go to http://www.isnare.com/distribution.php
- For more free-reprint articles go to http://www.isnare.com
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