Here is my workflow to preserve as much detail from RAWs when I'm not shooting HDR:
All of my adjustments are made in Adobe Camera Raw, and then I process using the "Image Processor" plug-in in Adobe Bridge.
1. I'll do a basic white balance adjustment to roughly where I want it and then apply the same white balance settings to all photos during the conversion. I usually don't bother to shoot with a locked white balance as there is no loss in setting a consistent white balance after the fact if shooting in RAW.
2. I do lens adjustments like distortion and chromatic aberration removal.
3. If I have a lot of shadow and highlight detail, I'll push shadows, pull highlights, and generally reduce the contrast of the image. This will get most of the pixel values out of the extremes and hopefully retain more of the data. Theoretically, a 16-bit lossless TIFF should keep a lot if not all of this detail, however, a dedicated RAW processor might do a better job of getting as much detail as possible out of everything.
4. I do shoot at locked exposures when I can, but PTGui should be able to handle basic exposure adjustments after the fact. As long as your EXIF data is maintained in your TIFFSs PTGui should know exactly how much to "push and pull" each image. If not, you can always manually adjust exposure (or make a script) to ensure that the exposure for each image is consistent during your RAW processing step.
-- For the automated PTGui route, open the advanced settings, go to Exposure/HDR, and you should be able to turn on the "Optimize Brightness" setting.
5. As a final step, when shooting my non-hdr panoramas, I use a feature in my camera called "highlight-weighted metering" (I have a Nikon D780, but other cameras also sometimes have this). This is a metering mode that sets exposure in such a way that none of the highlights are blown. That way I can extract all of the detail I need out of the shadows and have nothing lost. Though, this only really works well if your camera is iso-invariant.
Hope this is helpful to someone.