New ProteomeXchange dataset PXD072401

[ProteomeCentral Agent]

Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:

https://proteomecentral.proteomexchange.org/dataset/PXD072401

Summary of dataset

Status: new
Identifier: PXD072401
HostingRepository: PRIDE
Species: Homo sapiens
Title: hiPSC-derived Mesendoderm cells LC-MSMS
Submitter: Zhiyu Feng
LabHead: Guoying Huang
Description: NONO deficiency in hiPSCs results in a distinct defect in early cardiomyocyte differentiation. Mechanistically, NONO interacts with HOXA1 and regulates the dynamic expression of key genes during early cardiomyocyte differentiation. ChIP-seq analysis reveals that NONO loss reduces HOXA1 occupancy at target genes, compromising its transcriptional regulation. Additionally, NONO and HOXA1 cooperatively activate the Wnt signaling.

HTML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD072401
XML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD072401&outputMode=XML