New ProteomeXchange dataset PXD055169

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ProteomeCentral Agent

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Oct 17, 2025, 7:39:24 AM (yesterday) Oct 17
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Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:

https://proteomecentral.proteomexchange.org/dataset/PXD055169

Summary of dataset

Status: new
Identifier: PXD055169
HostingRepository: PRIDE
Species: Homo sapiens
Title: Cysteine-enabled Cleavability to Advance Cross-linking Mass Spectrometry for Global Analysis of Endogenous Protein-Protein Interactions
Submitter: Fenglong Jiao
LabHead: Lan Huang
Description: We have employed the sulfoxide-based cleavability to establish a novel cysteine-based MS-cleavable XL-MS platform, enabling proteome-wide PPI analysis using non-cleavable heterobifunctional K-C linkers. The effectiveness of the newly established platform has been demonstrated using three commercially available and non-cleavable NHS ester-haloacetamide heterobifunctional cross-linkers to map in vivo PPIs from HEK 293 cells.

HTML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD055169
XML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD055169&outputMode=XML

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