Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:
https://proteomecentral.proteomexchange.org/dataset/PXD055169
Summary of dataset
Status: new
Identifier: PXD055169
HostingRepository: PRIDE
Species: Homo sapiens
Title: Cysteine-enabled Cleavability to Advance Cross-linking Mass Spectrometry for Global Analysis of Endogenous Protein-Protein Interactions
Submitter: Fenglong Jiao
LabHead: Lan Huang
Description: We have employed the sulfoxide-based cleavability to establish a novel cysteine-based MS-cleavable XL-MS platform, enabling proteome-wide PPI analysis using non-cleavable heterobifunctional K-C linkers. The effectiveness of the newly established platform has been demonstrated using three commercially available and non-cleavable NHS ester-haloacetamide heterobifunctional cross-linkers to map in vivo PPIs from HEK 293 cells.
HTML_URL:
https://proteomecentral.proteomexchange.org/dataset/PXD055169
XML_URL:
https://proteomecentral.proteomexchange.org/dataset/PXD055169&outputMode=XML