New ProteomeXchange dataset PXD074283

[ProteomeCentral Agent]

Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:

https://proteomecentral.proteomexchange.org/dataset/PXD074283

Summary of dataset

Status: new
Identifier: PXD074283
HostingRepository: iProX
Species: Mus musculus
Title: Quantitative Proteomics of mPFC Tissue in a Vascular Cognitive Impairment Mouse Model
Submitter: Yue Hei
LabHead: Yue Hei
Description: Deep quantitative proteomic profiling of bilateral medial prefrontal cortex (mPFC) from control (ctrl), vascular cognitive impairment (VCI, model) and EVs treatment (test) mice (3 biological replicates each). Proteins extracted with RIPA + inhibitors, quantified by BCA, processed via FASP, digested with trypsin, labeled with TMT-16plex, fractionated by high-pH RP, and analyzed on nanoLC-Q Exactive HF-X (DDA, 120k/15k resolution). Raw files searched against Mus musculus UniProt in PD 3.0/Mascot (FDR ≤1%). Differentiation criteria: fold-change >1.2, p<0.05 (Perseus).

HTML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD074283
XML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD074283&outputMode=XML