Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:
https://proteomecentral.proteomexchange.org/dataset/PXD070941
Summary of dataset
Status: new
Identifier: PXD070941
HostingRepository: PRIDE
Species: Homo sapiens
Title: Identification of Molecularly Targeted Therapy-Induced Immunopeptidome in Diffuse Midline Glioma (DMG)
Submitter: Habeebah Owolabi
LabHead: Stefanie Galban
Description: We used MHC-I immunopeptidomics to study how MTX-241F, a selective EGFR/PI3K inhibitor, alters antigen presentation in diffuse midline glioma (H3K27M) and glioblastoma xenografts. MHC-I–bound peptides from vehicle- and drug-treated tumors were profiled by LC–MS/MS to identify tumor- and treatment-specific peptides, including candidate brain-enriched biomarkers and immunotherapy targets.
HTML_URL:
https://proteomecentral.proteomexchange.org/dataset/PXD070941
XML_URL:
https://proteomecentral.proteomexchange.org/dataset/PXD070941&outputMode=XML