New ProteomeXchange dataset PXD065737

[ProteomeCentral Agent]

Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:

https://proteomecentral.proteomexchange.org/dataset/PXD065737

Summary of dataset

Status: new
Identifier: PXD065737
HostingRepository: PRIDE
Species: Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
Title: Phytotoxic peptides released by the phytopathogenic fungus Botrytis cinerea as a potential novel mechanism of fungal infection
Submitter: ALMUDENA ESCOBAR NIÑO
LabHead: Francisco Javier Fernández Acero
Description: Botrytis cinerea, the causal agent of gray mold and noble rot, is a phytopathogenic fungus with a scientific and economic relevance due to its effects in agriculture. This fungus employs various molecular tools, such as enzymes and secondary metabolites, to infect and colonize plant tissues. Pathogenicity and virulence factors are identified, highlighting their role in the infectious cycle. Our approach presents the description of a new infection mechanism in the phytopathogenic fungus Botrytis cinerea, based on the production of bioactive peptides. Those peptides were isolated from cultures with glucose (constitutive stage) and tomato (virulence inductor), and showed significant effects on virulence, suggesting a crucial function in the fungus-plant interaction. Biochemical and genetic analysis methods were employed to determine the expression of genes involved in peptide production, highlighting the potential for de novo peptide synthesis and degradation of parental pr
oteins. The results indicate that B. cinerea has significant biotechnological potential, as it can generate peptides of interest for industrial and pharmaceutical applications. This work is pioneering in describing the peptidome of a phytopathogenic fungus and suggests new strategies for controlling microbial infections.

HTML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD065737
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