New ProteomeXchange dataset PXD066216

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Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:

https://proteomecentral.proteomexchange.org/dataset/PXD066216

Summary of dataset

Status: new
Identifier: PXD066216
HostingRepository: PRIDE
Species: Escherichia coli
Title: E. coli CFT073 protein expression at t= 4 hours after a temperature upshift from 23˚C to 37˚C (M9 minimal glycerol medium, exponential phase growth)
Submitter: Christine White-Ziegler
LabHead: Christine White-Ziegler
Description: We investigated the effect of a temperature shift from 23˚C to 37˚C, mimicking the temperature transition experienced by a microbe as it enters a human host. This strategy allowed the exploration of protein expression changes in a short term response to a temperature upshift and to characterize the suite of proteins required to respond to a 37˚C host in the first few hours. We demonstrate that a significant number of proteins are rapidly altered in expression within hours after a temperature shift. Many of these proteins are related to adhesion, biofilm formation, and immune evasion, suggesting that temperature serves as a sentinel cue to predict and prepare for niche adaptation in the host.

HTML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD066216
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