New ProteomeXchange dataset PXD072766

[ProteomeCentral Agent]

Dear ProteomeXchange subscriber, a new ProteomeXchange dataset is being announced. To see more information, click here:

https://proteomecentral.proteomexchange.org/dataset/PXD072766

Summary of dataset

Status: new
Identifier: PXD072766
HostingRepository: PRIDE
Species: Homo sapiens
Title: An Oleuropein-based olive leaf extract enhances the muscle mitochondrial response to acute moderate – but not maximal – intensity exercise in humans
Submitter: Loïc Dayon
LabHead: Loïc Dayon
Description: Sprint interval exercise (SIE) induces mitochondrial adaptations in skeletal muscle, comparable to or greater than moderate-intensity continuous exercise (MICE), despite lower training volume. These effects are partly due to enhanced mitochondrial bioenergetics, including increased Ca²⁺ uptake and pyruvate dehydrogenase (PDH) activation. Oleuropein (OLE), a compound from olive leaf extract, also promotes mitochondrial Ca²⁺ uptake and PDH activation in mice. The current study tested whether OLE could enhance these adaptations in humans during MICE or SIE. In a double-blind crossover design, healthy males performed either MICE or SIE with OLE supplementation. To elucidate the acute molecular response of skeletal muscle following exercise, we performed mass spectrometry-based proteomic analysis.

HTML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD072766
XML_URL: https://proteomecentral.proteomexchange.org/dataset/PXD072766&outputMode=XML