Issue with mutation position in protein paint

[Xiu L]

Hi all! When looking at DPF1 in protein paint, the mutation positions seem to all be shifted in the lollipop plot.

For example here, R76 is marked at a position around 49/50. It looks like all positions are shifted left. Any idea what's going on here? I've checked that this is the canonical sequence, and I have no problem looking at other proteins. Only have had issues with DPF1.

Thank you!

[Karishma Gangwani]

Hi Xiu L, 

Thanks for bringing this to our attention. Could you tell me what isoform (starts with NM_), genome (hg38 or hg19) and dataset are you looking at for that gene?

Best, 

Karishma

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[Xiu L]

Hi Karishma,

It's NM_001135155, hg38, GDC.

Thank you!

[Karishma Gangwani]

Thanks. We will keep you informed once we have resolved the issue. 

Best,
Karishma Sanjay Gangwani, PhD
SJCRH

[Xiu L]

Thank you!

[Xiu L]

Hi Karishma,

I'd also like to add that the canonical human DPF1 protein sequence (Q92782-2) should have 387 AA - in protein paint by default it shows as 388 AA.

Thank you!