Sulforaphane
Philip Blair
Sulforaphane SFN is a dietary phytochemical in broccoli, cabbage, and can be considered a food, dietary supplement, or a drug. There is good evidence from clinical studies, that sulforaphane counteracts oxidative stress, defects in reduced glutathione synthesis, mitochondrial dysfunction and low oxidative phosphorylation, increased lipid peroxidation, and neuroinflammation. Sulforaphane crosses the blood-brain-barrier and quickly reach the brain to exert its protective effects. Several preclinical studies show SFN reduces pain. Other studies have shown it effective in cancer of breast, lung, prostate, brain glioma and lung. Avmacol® is a highly absorbed form of SFN that has been shown effective in autism for less than $50/m. Dosage is four crushable tablets per day.