Problem regarding protein modelling and interactions

[R A J Rajkishore]

Hello Everyone , 

I have a protein LOXL1 (whose 3D structure has not yet been modelled/predicted so far).

For modelling ,this protein carries only 10% Query Coverage and Structure Coverage of 30%.

Is there any source for predicting the homology structure of this protein.

Also , it contains 57% of disordered region amino acids.

And, this protein in combination with Fibulin 5 protein causes pseudoexfoliation.

Also there is the same condition of Fibulin 5 protein structure as of LOXL1.

Is there any essential requirements for doing Protein protein Interaction between Fibulin 5 and LOXL1.

I have compared this both two proteins in Blast2 for proteins as it is showing 50% identity.

Also this both have 40-50% mutant regions similarity.

Please guide me .. How to model LOXL1 and what to do in case of Protein Protein Interaction between these two.

I have finished modelling via online tools like Phyre2 , I-Tasser , Swiss Model and Rosetta. But cant predict the better output structure.

Waiting for response .. !!

With regards , 

Rajkishore Mohapatra

Lab of Computational Biology, 

Center for DNA Fingerprinting and Diagnostics (DBT),

Hyderabad,India