This question was answered on our Slack channel. Copying the answer here so it pops up in future searches...
Our media reads stat is in cachelines, So you will see a 4X amplification on our current Optane PMem products. Typically for writes you will see 2X but sometimes more or less depending on merging of writes. We do have a 256B read buffer so sequential cachelines might hit that buffer and not result in an amplification.