Dependence on PBC corrections

[Joshua Katta]

Hello, i am a beginner in learning post trajectory analysis and i have a question. do  global structural properties like RMSD RG depend on fixing the periodic boundary condition artifacts of the simulation or not. do i have to fix pbc and center the molecule before i run rmsd rg etc or does plumed does it for me. idk i have just started learning plumed and i had a doubt.