SKAT info

[zdw...@gmail.com]

Hello,

I am interested in using SKAT that is incorporated within PLINK/SEQ for gene based analysis. I was wondering if you can point me in the direction of some file or overview that details the options that can be used with the SKAT test. I am particularly interested in assigning weights to my variants based on functionality derived from an annotation program (such as ANNOVAR). I know this can be done by providing a custom weight file in the SKAT R package, so I wanted to see if a similar mechanism needs to happen in PLINK/SEQ. 

Thank you for any assistance you can provide me.

Best,

Zach W.