plink for haploid candida auris genome

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Naama Yefet

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Jul 31, 2025, 9:38:37 AMJul 31
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hi! i am running an association study on candida auris isolated derived from skin and blood to find variants associated with violence. i would like to know if plink is the right tool for that , if it can handle haploid genome and if so, what are the adaptations that need to be made? 

Chris Chang

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Jul 31, 2025, 10:08:12 AMJul 31
to Naama Yefet, plink2-users
You can use the --chr-set flag to specify a haploid genome.

There are some standard diploid-dataset quality control steps (--hwe, --check-sex) which don't work for haploid genomes; and they will tell you that they don't work if you try them.
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