Hi, Sorry for the delay.
Yes, this registration was not successful. In general, the bladder can be difficult to match.
I can offer the following general suggestions:
1) While tuning the parameters, run a single stage at low resolution. If the first stage doesn't work, additional stages won't help.
2) It can help to adjust the contrast prior to registration to highlight difference between organs. For example, if the bladder has HU 40 and surrounding fat has HU -80, you can accentuate intensity differences between them.
3) In worst case, use landmarks to manually improve.
Greg