How to use purchased KEGG

[徐军明]

Hello, the SC reference library uses EggNOG v5 annotations. Is the KEGG version older? We have purchased KEGG, but I don't know if the process of using the new version of KEGG in picrust2 is complicated.

[Robyn Wright]

Hi there,

Does the paid version of KEGG allow you to annotate genomes with it? If not, then no - you could use the KEGG pathway mapping if you wanted to use those instead of MetaCyc. If yes, then you could annotate all of the genomes included in the database (you can see how to do this on the page for adding custom traits to the database here) - whether it's worth doing this for you will depend on the computational resources you have available as well as how much those more recent KEGG annotations matter to your research. 

Best wishes,

Robyn