Hi, Mike - Sorry, I didn't get a notification that you'd responded!
Here's my setup:

The fan on the left is the print cooling fan, the fan in back is the hot end cooling fan. I tried the unrestricted fan 'air guide' B3 recommends, and had significant issues. This one works better - the cooling fins stay cool to the touch.
I'm printing PLA and PETG; the problem is universal. Filament currently on the printer is Inland PLA, while I also have Hatchbox PLA and PETG, Inland PLA and PETG, Madesolid PET+, and eSun PLA and PETG. I always measure my filament with calipers; all of these spools are consistent throughout a couple of meters. All of these spools work perfectly well on my Replicator Dual.
I'm printing PLA at 205 right now. I've tried speeds ranging from 50mm/s to 250mm/s, and temperatures ranging from 205-240 (PLA) and 215-250(PETG).
If I turn off retraction, I don't have jams, but I don't get useful prints, either (too much stringing and oozing - I think I hate bowden extruders). I've experimented with all kinds of settings, but here is what I was using on my last go-round, where I had a jam (every print I've made that was longer than a few minutes had a jam):

I'm using Simplify3D, though I've tried with Repetier-Host as well with similar results. I still get jams with every print.
Any thoughts?
Thanks!