Aptamer tertiary structure

[Juan Manuel Aceves-Hernandez]

Hi, I am working wi th ADN aptamer and got the sequence en the secondary structure. I wonder if somebody can help to get the tertiary structure as Protein Data Bank file or format , in order to study more friendly the interaction with some proteins?. I will Apprecite deeply your valuable help. Sincerely 

[Powell, Harold]

Hi

The best I can do at the moment is to suggest RoseTTAfoldDNA as described in this paper from the Baker group - Baek, M., McHugh, R., Anishchenko, I. et al. Accurate prediction of protein–nucleic acid complexes using RoseTTAFoldNA. Nat Methods 21, 117–121 (2024), doi https://doi.org/10.1038/s41592-023-02086-5.

If you need more information, then I would contact Frank DiMaio by e-mail directly since he's the Corresponding Author.

Best wishes

Harry