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Agenor Ramadan

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Aug 3, 2024, 2:35:12 PM8/3/24
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The tables below provide a consolidated overview for which operating systems, platforms, BeyondTrust product integrations, and third party product integrations are supported with which BeyondInsight and Password Safe component or functionality.

BeyondTrust is the worldwide leader in intelligent identity and access security, enabling organizations to protect identities, stop threats, and deliver dynamic access. We offer the only platform with both intelligent identity threat detection and a privilege control plane that delivers zero-trust based least privilege to shrink your attack surface and eliminate security blind spots.

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As the number of cloud platforms supporting scientific research grows, there is an increasing need to support interoperability between two or more cloud platforms. A well accepted core concept is to make data in cloud platforms Findable, Accessible, Interoperable and Reusable (FAIR). We introduce a companion concept that applies to cloud-based computing environments that we call a Secure and Authorized FAIR Environment (SAFE). SAFE environments require data and platform governance structures and are designed to support the interoperability of sensitive or controlled access data, such as biomedical data. A SAFE environment is a cloud platform that has been approved through a defined data and platform governance process as authorized to hold data from another cloud platform and exposes appropriate APIs for the two platforms to interoperate.

As the number of cloud platforms supporting scientific research grows1, there is an increasing need to support cross-platform interoperability. By a cloud platform, we mean a software platform in a public or private cloud2 for managing and analyzing data and other authorized functions. With interoperability between cloud platforms, data does not have to be replicated in multiple cloud platforms but can be managed by one cloud platform and analyzed by researchers in another cloud platform. A common use case is to use specialized tools in another cloud platform that are unavailable in the cloud platform hosting the data. Interoperability also enables cross-platform functionality, allowing researchers analyzing data in one cloud platform to obtain the necessary amount of data required to power a statistical analysis, to validate an analysis using data from another cloud platform, or to bring together multiple data types for an integrated analysis when the data is distributed across two or more cloud platforms. In this paper, we are especially concerned with frameworks that are designed to support the interoperability of sensitive or controlled access data, such as biomedical data or qualitative research data.

There have been several attempts to provide frameworks for the interoperating cloud platforms for biomedical data, including those by the GA4GH organization3 and by the European Open Science Cloud (EOSC) Interoperability Task Force of the FAIR Working Group4. A key idea in these frameworks is to make data in cloud platforms findable, accessible, interoperable and reusable (FAIR)5.

The authors have developed several cloud platforms operated by different organizations and were part of a working group, one of whose goals was to increase the interoperability between these cloud platforms. The challenge is that even when a dataset is FAIR and in a cloud platform (referred to here as Cloud Platform A), in general the governance structure put in place by the organization sponsoring Cloud Platform A (called the Project Sponsor below) requires that sensitive data remain in the platform and only be accessed by users within the platform. Therefore, even if a user was authorized to analyze the data, there was no simple way for the user to analyze the data in any cloud platform (referred to here as Cloud Platform B), except for the single cloud platform operated by the organization (Cloud Platform A).

There are several reasons for this lack of interoperability between cloud platforms hosting sensitive data: First, as just mentioned, for many cloud platforms, it is against policy to remove data from the cloud platform; instead, data must be analyzed within the cloud platform.

Second, in some cases, to manage the security and compliance of the data, often there is only a single cloud platform that has the right to distribute controlled access data; other cloud platforms may contain a copy of the data, but by policy cannot distribute it.

Fourth, once a Sponsor has approved a single cloud platform as authorized to host data and to analyze the hosted data, there may be a perception of increased risk to the Sponsor in allowing other third party platforms to be used to host or to analyze the data. Because of this increased risk, there has been limited interoperability of cloud platforms for controlled access data.

The consensus from the working group was that interoperability of data and an acceleration of research outcomes could be achieved if standard interoperating principals and interfaces could describe which platforms had the right to distribute a dataset and which cloud platforms could be used to analyze data.

In this note, we introduce a companion concept to FAIR that applies to cloud-based computing environments that we call a Secure and Authorized FAIR Environment (SAFE). The goal of the SAFE framework is to address the four issues described above that today limit the interoperability between cloud platforms. The cloud-based framework consisting of FAIR data in SAFE environments is intended to apply to research data that has restrictions on its access or its distribution or both its access and distribution. Some examples are: biomedical data3,6, including EHR data, clinical/phenotype data, genomics data, imaging data; social science data7 and administrative data8. We emphasize that the environment itself is not FAIR in the sense of5, but rather that a SAFE environment contains FAIR data and is designed to be part of a framework to support the interoperability of FAIR data between two or more data platforms.

Also, SAFE cloud platforms are designed to support platform governance decisions about whether data in one cloud platform may be linked or transferred to another cloud platform, either for direct use by researchers or to redistribution. As we will argue below, SAFE is designed to support decisions between two or more cloud platforms to interoperate in the sense that data may be moved between them, but is not designed nor intended to be a security or compliance level describing a single cloud platform.

We assume that data is generated by research projects and that there is an organization that is responsible for the project. We call this organization the Project Sponsor. This can be any type of organization, including a government agency, an academic research center, a not-for-profit organization, or a commercial organization.

In the framework that we are proposing here, the Project Sponsor sets up and operates frameworks for (1) data governance and (2) platform governance. The Project Sponsor is ultimately responsible for the security and compliance of the data and of the cloud platform. Data governance includes: approving datasets to be distributed by cloud platforms, authorizing users to access data, and related activities. Platform governance includes: approving cloud platforms as having the right to distribute datasets to other platforms and to users and approving cloud platforms as authorized environments so that the cloud platforms can be used by users to access, analyze, and explore datasets.

By controlled access data, we mean data that is considered sensitive enough that agreements for the acceptable use of the data must be signed. One between the organization providing the data (the Data Contributor) and the Project Sponsor and another between researchers (which we call Users in the framework) accessing the data and the Project Sponsor. Controlled access data arises, for example, when research participants contribute data for research purposes through a consent process, and a researcher signs an agreement to follow all the terms and conditions required by the consent agreements of the research participants or by an Institutional Review Board (IRB) that approves an exemption so that consents are not required.

As is usual, we use the term authorized user, as someone who has applied for and been approved for access to controlled-access data. See Table 1 for a summary of definitions used in this paper.

One of the distinguishing features of our interoperability framework is that we formalize the concept of an authorized environment. An authorized environment is a cloud platform workspace or computing / analysis environment that is approved for the use or analysis of controlled access data.

Below we describe some suggested processes for authorizing environments, including having their security and compliance reviewed by the appropriate official or committee determined by the platform governance process. We also argue that the environments should have APIs so that they are findable, accessible and interoperable, enabling other cloud platforms to interoperate with it. As mentioned above, we use the acronym SAFE for Secure and Authorized FAIR Environments to describe these types of environments. In other words, a SAFE environment is a cloud platform that has been approved through a platform governance process as an authorized environment and exposes an API enabling other cloud platforms to interact with it (Fig. 1).

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