Yes.
Install Oracle Instant Client (you need the sdk, client, sqlplus).
Untar it somewhere accessible from your web user.
Add untarred_dir/bin to PATH and export it.
Run sqlplus with the correct args to connect to your Oracle to prove the
client works.
Download DBD::Oracle. Assuming Unix or Linux, set LD_LIBRARY_PATH (or
equivalent) to point to the dir you untarred instant client into. Do the
usual with DBD::Oracle - perl Makfile.PL, make, make test, make install.
Write Perl code using DBI module to issue query and get results.
Martin