, what did you learn about COPD Management?

[ePulmonlogy Review]

View this email in your browser Post-Assessment Dear Colleague, Thank you for participating in ePulmonology Review. We hope you have enjoyed Issues 3 & 4 on COPD, Triple Therapy, GOLD, and COVID: State-of-the-ART Management (Early 2022) with our guest author Nirupama Putcha, MD, MHS. Please take our post-assessment here. Take Post-Assessment Now If you have not yet read the newsletter or listened to the podcast, please visit our newsletter archive here. In case you forgot, here are the key takeaways from ePulmonology Review Issues 3 & 4: Results from the ETHOS trial indicate that 160 µg budesonide and 320 µg budesonide triple therapy more effectively reduces the rate of moderate or severe exacerbations in COPD than dual therapy with a LAMA/LABA or ICS/LABA combination. These findings align with those collected from the IMPACT, TRILOGY, and TRIBUTE clinical trials.  Separate findings from a post hoc analysis of the ISOLDE trial suggest that changes in blood eosinophil counts after ICS administration may predict clinical response to therapy in patients with COPD and increase in eosinophil after ICS was associated with higher risk of exacerbation with ICS treatment.   Patient-level data for people with COPD linked with the OpenSAFELY platform based in the United Kingdom do not indicate that regular ICS use confers a protective effect against SARS-CoV-2. Observed increased risks of death were likely attributable to unmeasured confounding, supporting the suggestion to continue treating COPD as before the SARS-CoV-2 pandemic.  Supplementation with vitamin D can help reduce the rate of moderate or severe exacerbations in patients with a preexisting deficiency (<25 nmol/L). Clinicians should consider testing vitamin D status in patients with COPD, as such a deficiency is prevalent in this population.   Activity Directors Gregory B. Diette, MD Read bio Christine Smith, RN, MSN Read bio The Johns Hopkins University School of Medicine Office of Continuing Medical Education 720 Rutland Avenue, Turner 20 Baltimore, Maryland 21205-2195 Phone: (410) 502-9634 Fax: (866) 510-7088 E-mail: [email protected] Website: hopkinscme.cloud-cme.com/aph.aspx The Institute for Johns Hopkins Nursing 600 North Wolfe Street, Admin. 308 Baltimore, Maryland 21287 Email: [email protected] Website: https://www.hopkinsmedicine.org/institute_nursing/index.html Please add this email to your address book or safe senders list to ensure future emails. DKBmed, LLC 122 West 26th Street Suite 1100 New York, NY 10001 Phone: (646) 336-6495

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