Numbering scheme for partis?

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Lmar Babrak

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Jan 14, 2021, 5:57:12 AM1/14/21
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Hi, 
What numbering scheme (ie IMGT, Kabat, Clothia) do you use to dilineate framework and cdr3 regions? Sorry if you've already answered but I haven't been able to find it.

Thanks
Lmar

Duncan Ralph

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Jan 14, 2021, 10:52:26 AM1/14/21
to Lmar Babrak, partis
Hi,

We use IMGT numbering, with the caveats: 1) positions in partis output files all use 0-based indexing and 2) the partis key "cdr3_length" includes both conserved codons, whereas in the imgt terminology this should really be called "junction" length (sorry... I've looked at swapping these but it'd just be too error-prone).

And thanks for pointing out the ambiguity, I'm making a note to add to the manual.

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