Dear all,
I want to study parallel evolution, but foreground species are interlaced with background species in the tree, I have run codeml using two approaches,
2. extract all parallel clades, and then run BSM for each clade seperately, finally find intersection in the resulting positively selected sites of each clade, which is a method used in a PNAS paper: "Comparative genomics reveals convergent evolution between the bamboo-eating giant and red pandas".
I tried both methods, but the results of two approaches were different, I am not sure what cause the discrepancy and which approach is the best strategy, can you help me with this,
Thank you
Dong