Dear Doctor,
Greetings from Intas Pharmaceuticals Ltd.
I am herewith sharing treatment algorithm along with key recommendations
from the recently published
JNC-8 Guidelines for management of high blood pressure in adults.
JNC VIII full text-
http://jama.jamanetwork.com/data/Journals/JAMA/0/jsc130010.pdf
JNC VIII Treatment algorithm

JNC 8 RECOMMENDATIONS for management of high blood pressure in adults:-
-
In people over the age of 60, blood pressure target should be below 150/90 mmHg. Pharmacological therapy should be started if blood pressure is above this value.
-
If a patient achieves a blood pressure target lower than 150/90 and even lower than 140/90 mmHg, but tolerates this blood pressure and the medication without side-effects, no change is needed. In other words, there
is no need to reduce medication dose to allow the blood pressure to go up.
-
In people under the age of 60, blood pressure target should be below 140/90 mmHg. Medical therapy should be started to achieve this target.
-
In adults (over the age of 18) who have chronic kidney disease the target blood pressure should be less than 140/90 mmHg. Treatment should include an ACE-inhibitor or angiotensin receptor blocker.
-
In adult diabetics, blood pressure should be lower than 140/90 mmHg and medication should be administered to achieve this. This recommendation is more lenient than in the previous version of the guidelines.
-
Choice of anti-hypertension medication is not very important in the non-black population. Options include thiazide diuretics, calcium channel blockers, ACE-inhibitors or angiotensin receptor blockers. ACE-inhibitors
and ARB’s should not be used in conjunction in the same patient.
-
In black people, including those with diabetes, treatment of blood pressure should include a thiazide diuretic or a calcium channel blocker.
-
Treatment of blood pressure should escalate on a monthly basis. This can include either increasing drug dose or adding another drug from a different class (again – ACE-I and ARB’s should not be combined). Interestingly,
lifestyle modifications are presented in JNC 8 as an adjunct to medical therapy, and not as a replacement (specifically in the algorithm on page E10).
-
Starting a combination of two medications may be considered in patients in whom blood pressure upon presentation is greater than 160/100 mmHg or at least 20/10 mmHg above target blood pressure.
We hope that the provided information would be of your interest.
Please revert on this mail for further information.
Awaiting your valuable feedback & suggestions.
Thanks and regards,
?
Dr. Dixit Patel, MD
Medical Advisor,
Intas Pharmaceuticals Ltd.




Note :
In case you are not interested to receive this scientific updates, please reply to this email stating “not interested”.