The Span parameter defines the width of the MsWing section you are modifying. By that, I mean the perpendicular distance between the root and tip airfoils in feet. You'll notice that if you adjust the sweep of the wing section, the distance between the two foils does not change. Keep in mind, however, that adjusting the dihedral of the wing will change the projected span (basically the silhouette as you look from the top down). Most aircraft dimensions list this value as the Span.
Hope this helps!