Most of OpenVSP is dimensionless -- the units are whatever you imagine them to be.
If you put in a 5 to describe a length - and you think it is in meters, then it is in meters. If you put in an accompanying 4 for a width, then the width is in meters and the area is 20 m^2. A volume would be in m^3, etc.
Some of the analysis tools in OpenVSP do start to care about units -- VSPAERO, Parasite Drag, FEAMesh among them -- each of those will have a means for you to tell OpenVSP what you think the units are.
In some cases, you will need to supply other information (density, material properties, etc). You will need to do so in consistent units.
Rob