I had the same problem as you Pat Lee, but for me the cause seemed to be that I had multiple monitors as someone mentioned before.
I got the program working when I first set my display settings to only have one monitor. Then I opened Opentoonz and fixed the monitors so I can use my Cintiq again.
1. Right click on desktop select "Display settings"
2. Set the Multiple displays option to 'show only on X' (Whichever is your main monitor)
3. Then apply
4. Start opentoonz and go change the multiple displays option back to 'extend these displays'
Hope it works!