Not sure if this is too late and you've already know what you're doing now but here we go:
Layers in Opentoonz are called "Levels", you can have multiple types of levels but the main one's you'd be using are "Toonz Vector" (Brush works like "Flash" if you've ever used it) and "Toonz Raster" (Brush works like "Photoshop").
Go to File>New Level (i'd say start with a raster) on a new scene and designate how many frames your thinking of having, if you're not bothered about duration just put your "End" frame to something like 30.
Do your rough animation (it's hard to get used to switching back between drawing and navigating the XSheet but you get used to it) on your raster layer, then....when you're ready, go to File > New Level, set it to Toonz Vector and start your inking.