OpenToonz is a Qt5 application, as such DPI sensitivity can be configured via Qt.
I fixed this issue by creating a system environment variable: QT_AUTO_SCREEN_SCALE_FACTOR=1
On Windows 10 you can do this by pressing the windows icon and typing "environment". Choose "Edit the system environment variables" (I have tested it and it works in both system or user environment variables).
On the window that appears, click the "Environment Variables" button and then click "New". Input QT_AUTO_SCREEN_SCALE_FACTOR for the variable name, and 1 for the variable value.
Now launch OpenToonz and enjoy!
It looks pretty simple to include this directly into the Qt code, so I'm going to see about submitting a code fix for this.