The best regular expression will probably depend on the context because they get used slightly differently in different places, but it looks like you're working with a Text Filter facet.
The first thing I'd try is:
^[^0-9]*$
which will restrict the entire cell value to zero or more non-numerics.
The Text Filter facet is more permissive than other contexts in that it'll match substrings by default, whereas GREL functions typically match the entire value (so you need to explicitly wrap your RE with .* on either side, if you want the more common substring style matching).
Tom