Problem Var (ln Response ratio) calculation openMEE

[Ander Yoldi Achalandabaso]

Dear researcher

First of all, thanks for the huge work done for openMEE development.

I am using it and  I am very grateful. However, I am having a problem with Variance of Ln Response Ratio calculation.

In the sheet, I have added for each study the raw mean value, standard deviation and sample size, either for the treatment and the control. Afterwards, I defined as continuous data the commented columns. But, when I try to calculate the effect size, selecting means and standard deviation, ln response ratio, in the next window I can not select the sample size. Therefore, after finishing the effect size calculation, I only got the ln response ratio and not the ln of the variance too.

How can I calculate the variance of the ln response ratio?

If not, I found the next formula that maybe I could run in excel and introduce manually in openMEE:

= St^2/ntXt^2 + Sc^2/ncXc^2

Where s is the standard deviation for treatment and control, n is the sample size (biological replicate) for treatment and control and X is the mean value for treatment and control.

Thanks in advance for your help. I would be very grateful if you could shed light on this regard,

Ander