Nanofactory

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technologiclee

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Nov 9, 2009, 4:37:55 AM11/9/09
to Open Manufacturing

With the efforts made by this group in Atomic Force Microscopes,
Focused Ion Beams, microfluidics, 3D printing, and lab on a chip, how
can we progress to a first generation of 'nanofactory'?

http://www.youtube.com/watch?v=zqyZ9bFl_qg


I will be starting a similar thread on DIY bio - focusing on the
ribosome.

http://www.youtube.com/watch?v=zqyZ9bFl_qg

technologiclee

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Nov 9, 2009, 6:47:41 AM11/9/09
to Open Manufacturing

Tools and components to build a first generation 'nanofactory':

DNA Oragami: An increasingly varied toolset:
http://www.dana-farber.org/abo/news/press/2009/scientists-create-custom-three-dimensional-structures-with-dna-origami.html

Pick and Place Nanotubes:
http://www.youtube.com/watch?v=r1ebzezSV6s
http://www.youtube.com/watch?v=6LOednv-nQ4

Focused Ion Beam to make tools: The lab that did this has a better
FIB..
http://www.youtube.com/watch?v=Y_VI-GIakcE

Adamantane Tooltips: This is the first component seen in the
Nanofactory Animation. Adamantane can be found in oil.
http://machine-phase.blogspot.com/search?q=adamantane

C64N2H7 Molecular Gear: An AFM controlled gear, something like this
with adamantane tips makes a deposition tool.
http://machine-phase.blogspot.com/2009/06/molecular-gear-published-in-nature.html

A paper on: A Minimal Toolset for Positional Diamond
Mechanosynthesis:
http://www.ingentaconnect.com/content/asp/jctn/2008/00000005/00000005/art00002


Heath Matlock

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Nov 10, 2009, 1:16:44 AM11/10/09
to openmanu...@googlegroups.com
On Mon, Nov 9, 2009 at 9:37 AM, technologiclee <technol...@gmail.com> wrote:
>
>
> With the efforts made by this group in Atomic Force Microscopes,
> Focused Ion Beams, microfluidics, 3D printing, and lab on a chip, how
> can we progress to a first generation of 'nanofactory'?

Stop depressing me please (I would put a smiley emoticon, but it is
kind of depressing). I don't know anyone on here who has made an AFM,
FIB or SEM. Also Lab-on-a-chip is an alternative way of mentioning
microfluidics. But there is progress, we've dabbled in 3D printing,
and have experimented with some tools like OpenFoam and Elmer, and
created micronfluidic devices using sharpies. I haven't seen anyone
share their work on creating an actual microfluidic chip, though
Jonathan Cline ( http://88proof.com/synthetic_biology/blog/ ) has done
some interesting work. My friend Evgeny and I have been talking about
a precision positioning system for the past year, he has actually made
some progress. Right now it's vaporware in the sense that it doesn't
work though, so don't expect much.

Probably the most significant factor preventing others from dedicating
their time to some of these projects is time and priorities. SKDB has
recently become my priority número uno, but there are a lot of neat
projects to work on (and hopefully they or similar projects can be
committed to SKDB eventually).

Here's a few (and I'll try to get back on-topic soon..):

SEM/FIB: discussion went nowhere (see diybio list)
AFM/STM: plenty of resources previously discussed
Brain Emulation: see previous post on topic and some of the
Singularity Institute 2009 videos (
http://www.vimeo.com/siai/videos/sort:oldest )and a roadmap published
awhile ago ( http://www.fhi.ox.ac.uk/Reports/2008-3.pdf)
the autonomous vehicle simulations
Launch a rocket into space: http://sugarshot.org/project_description.html
Various microfluidics chips to be made, for me I'd like to create one
with the PCB tech I have available at work (see the PCB microfluidics
papers on http://ybit.ath.cx/unsorted_papers/ or
http://adl.serveftp.org/papers/unsorted/ )

And wow, so many more to mention, but I'm not going to go on, I'll
just link you to a few half-heartedly slung together documents:

http://github.com/kanzure/skdb/blob/master/doc/proposals/trans-tech.yaml

http://gitorious.org/diyhplus/diyhplus_org/blobs/3b8bbab4d3fa488fbc8347943f6ba01f72395a5b/todo.org


So, with all that said...


> I will be starting a  similar thread on DIY bio - focusing on the
> ribosome.

I'd like to encourage you to continue this pursuance of creating a
nanofactory (or whatever you think needs attention) and continue
sharing along the way. The MEMS mailing list can at times be helpful.
And the papers and books found on many of the members' servers are
nice (the diy-h+/open manufacturing archive really needs to be get
going soon..).


--
Heath Matlock
+1 256 274 4225

Heath Matlock

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Nov 10, 2009, 1:39:41 AM11/10/09
to openmanu...@googlegroups.com
On Mon, Nov 9, 2009 at 11:47 AM, technologiclee
<technol...@gmail.com> wrote:
>
>
> Tools and components to build a first generation 'nanofactory':
>
> DNA Oragami: An increasingly varied toolset:
> http://www.dana-farber.org/abo/news/press/2009/scientists-create-custom-three-dimensional-structures-with-dna-origami.html

caDNANO is the software behind that:
http://cadnano.org/
It should make you cringe, but maybe this software isn't as terrible:
http://www.cdna.au.dk/index.php/software.html (just stumbled on it).


> A paper on: A Minimal Toolset for Positional Diamond
> Mechanosynthesis:
> http://www.ingentaconnect.com/content/asp/jctn/2008/00000005/00000005/art00002

Eek! That's wanting you to purchase it for $400, why? It's available
online for free:
www.molecularassembler.com/Papers/MinToolset.pdf

Lee Nelson

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Jan 1, 2010, 1:28:11 PM1/1/10
to openmanu...@googlegroups.com
> Tools and components to build a first generation 'nanofactory':
>
> DNA Oragami: An increasingly varied toolset:
> http://www.dana-farber.org/abo/news/press/2009/scientists-create-custom-three-dimensional-structures-with-dna-origami.html


Optical tweezers are being used to build objects
http://www.ieeexplore.ieee.org/xpl/freeabs_all.jsp?isnumber=27593&arnumber=1231713&count=121&index=15



Notice the gear-like objects in this picture. Can a machine be made with parts like this?
http://www.sciencedaily.com/images/2009/08/090806141524-large.jpg

 
caDNANO is the software behind that:
http://cadnano.org/
It should make you cringe, but maybe this software isn't as terrible:
http://www.cdna.au.dk/index.php/software.html (just stumbled on it).


Has anyone installed caDNAno on Ubuntu / Ludic?
I have Adobe AIR installed but it will not start caDNAno


Has anyone used SARSE to make the nanobox? If so do you have the file?
http://medgadget.com/archives/2009/05/smart_nanobox_built_out_of_dna_origami.html
http://www.natureprotocols.com/2009/05/07/dna_origami_design_of_3d_nanos.php

This box has a controllable lid - this is a simple machine and can also serve as an enclosure.


What is the deal with science software and 'non-one-click-installs'? Can anyone make this easier for the community to use?
http://sarse.ku.dk/doc/install.txt

Bryan Bishop

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Jan 1, 2010, 1:41:20 PM1/1/10
to openmanu...@googlegroups.com, kan...@gmail.com
On Fri, Jan 1, 2010 at 12:28 PM, Lee Nelson <technol...@gmail.com> wrote:
> What is the deal with science software and 'non-one-click-installs'? Can
> anyone make this easier for the community to use?
> http://sarse.ku.dk/doc/install.txt

Looks pretty easy to me:

echo -e '\nPATH=$PATH:~/sarse-<version>/bin' >> .bashrc
source .bashrc
cd /usr/local
tar xpzf <download-directory>/sarse-<version>.tar.gz

Anyway, this is why .deb and .rpm was made.

- Bryan
http://heybryan.org/
1 512 203 0507

Lee Nelson

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Jan 1, 2010, 1:51:10 PM1/1/10
to openmanu...@googlegroups.com


Anyway, this is why .deb and .rpm was made.

Can you send a link to the SARSE .rpm?

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